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坐骨结节结核作为臀痛的罕见病因:9例病例系列报道并文献复习

Tuberculosis of ischial tuberosity as a rare cause of gluteal pain: A case series of 9 patients with review of literature.

作者信息

Jain Vijay Kumar, Iyengar Karthikeyan P, Rana Nipun, Agarwal Anil, Botchu Rajesh

机构信息

Professor, Department of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, 110001, India.

Trauma and Orthopaedic Surgeon, Southport and Ormskirk NHS Trust, Southport, PR8 6PN, UK.

出版信息

J Clin Orthop Trauma. 2022 Mar 31;28:101852. doi: 10.1016/j.jcot.2022.101852. eCollection 2022 May.

Abstract

BACKGROUND

Osteo-articular infection of the ischial tuberosity is a rare cause of gluteal pain.

METHODS

A retrospective clinico-radiological review of nine patients with infection of the ischial tuberosity was undertaken. The spectrum of presenting features, diagnostic challenges, radiological findings with particular emphasis on Magnetic resonance imaging (MRI) and clinical course was reviewed.

RESULTS

All the 9 patients (5 male: 4 female) aged between 8 and 50 years of age (mean 15.3 years) developed insidious onset of buttock pain over a period of weeks to months with difficulty in walking. Microbiological and/or histopathological confirmation of infection was undertaken in all cases. Complementary MRI revealed diffuse bone marrow signal hypointense or isointense on T1-weighted and hyperintense on T2-weighted and STIR images. MRI was able to provide anatomic details of soft tissue lesions and extensions. MRI illustrated the sinus tract in one patient. Ultrasound imaging allowed diagnostic and therapeutic management of in 3 patients.

CONCLUSION

Tuberculosis of ischial tuberosity can be a rare cause of gluteal pain. Delay in diagnosis could be due to an indolent natural history, unusual presentation and clinical features. A high index of suspicion especially in endemic areas with complementary imaging and microbiological or histopathological confirmation of infection is necessary for definitive diagnosis. Targeted treatment under the umbrella of Anti-Tubercular Therapy is crucial in achieving successful clinical outcome.

摘要

背景

坐骨结节骨关节炎感染是臀痛的罕见原因。

方法

对9例坐骨结节感染患者进行回顾性临床放射学研究。回顾了临床表现、诊断挑战、放射学表现,尤其着重于磁共振成像(MRI)以及临床病程。

结果

所有9例患者(5例男性,4例女性)年龄在8至50岁之间(平均15.3岁),在数周数月内逐渐出现臀部疼痛,并伴有行走困难。所有病例均进行了感染的微生物学和/或组织病理学确诊。辅助MRI显示,在T1加权像上骨髓弥漫性信号减低或等信号,在T2加权像和短TI反转恢复(STIR)像上为高信号。MRI能够提供软组织病变及其延伸的解剖学细节。MRI显示了1例患者的窦道。超声成像有助于3例患者的诊断和治疗管理。

结论

坐骨结节结核可能是臀痛的罕见原因。诊断延迟可能是由于其自然病程隐匿、表现及临床特征不寻常。对于确诊,尤其是在流行地区,必须高度怀疑,并辅以影像学检查以及感染的微生物学或组织病理学确诊。在抗结核治疗的框架下进行针对性治疗对于取得成功的临床疗效至关重要。

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本文引用的文献

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An unusual case of gluteal pain - Case report and review of literature.一例罕见的臀痛病例——病例报告及文献综述
J Clin Orthop Trauma. 2021 Jun 30;20:101487. doi: 10.1016/j.jcot.2021.101487. eCollection 2021 Sep.
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J Bone Jt Infect. 2017 Oct 9;2(4):184-193. doi: 10.7150/jbji.21692. eCollection 2017.
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Gluteal pain in athletes: how should it be investigated and treated?运动员的臀肌疼痛:应如何进行检查和治疗?
Rev Bras Ortop. 2015 Jul 18;50(4):462-8. doi: 10.1016/j.rboe.2015.07.002. eCollection 2015 Jul-Aug.
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Tuberculosis of the pubic symphysis: four unusual cases and literature review.耻骨联合结核:四例不常见病例报告并文献复习。
Clin Orthop Relat Res. 2013 Oct;471(10):3372-80. doi: 10.1007/s11999-013-3037-0. Epub 2013 May 14.
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Spinal tuberculosis: a review.脊柱结核:综述
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