Namazi Mohammad Hasan, Mazloomi Seyede Salimeh, Kalate Aghamohammadi Mohammad
Department of Cardiology, Moddares Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Internal Medicine, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arch Acad Emerg Med. 2022 Feb 14;10(1):e16. doi: 10.22037/aaem.v10i1.1466. eCollection 2022.
TIMI (Thrombolysis in Myocardial Infarction) score is a model for predicting the severity of vascular diseases. This study aimed to evaluate the correlation between this score and the number of vessels involved in patients with Unstable Angina (UA) or Non-ST Elevation Myocardial Infarction (NSTEMI).
This prospective cross-sectional study was designed to evaluate the correlation between TIMI score, and the number of vessels involved in the angiographic study of NSTEMI and UA patients presenting to emergency department.
297 patients with the mean age of 62.16±36.59 years were entered (58.2% male; 193 (65%) UA and 104 (35%) NSTEMI). The Mean TIMI score among patients was 3.21±1.55. Based on the TIMI score, patients were categorized into 3 groups. 105 (35.35%) patients had a TIMI score of 0 to 2, 120 (40.40%) had a score of 3 to 4, and 72 (24.24%) had a score of 5 to 7. Patients with a TIMI score of 5 to 7 had a greater likelihood of three-vessel coronary artery disease compared to patients with a TIMI score of 3 to 4 (OR: 5.34, 95% CI: 2.64 to 10.80; p < 0.0001) or those with a TIMI score of 0 to 2. (OR: 29.45, 95% CI: 12.87 to 67.37; p < 0.0001). Two-vessel coronary artery disease was more likely to be found in patients with a TIMI score of 3 to 4 or those with a score of 5 to 7 compared to patients with a TIMI score of 0 to 2 (OR: 3.69, 95% CI: 1.60 to 8.51; p <0.0001 and OR: 2.67, 95% CI: 1.04 to 6.82; p = 0.04, respectively).
There is a direct and significant correlation between TIMI score and the number of coronary vessels involved in patients presenting to emergency department following UA or NSTEMI.
心肌梗死溶栓（TIMI）评分是一种预测血管疾病严重程度的模型。本研究旨在评估该评分与不稳定型心绞痛（UA）或非ST段抬高型心肌梗死（NSTEMI）患者受累血管数量之间的相关性。
本前瞻性横断面研究旨在评估TIMI评分与急诊科就诊的NSTEMI和UA患者血管造影研究中受累血管数量之间的相关性。
纳入297例平均年龄为62.16±36.59岁的患者（男性占58.2%；193例（65%）为UA，104例（35%）为NSTEMI）。患者的平均TIMI评分为3.21±1.55。根据TIMI评分，患者被分为3组。105例（35.35%）患者的TIMI评分为0至2分，120例（40.40%）评分为3至4分，72例（24.24%）评分为5至7分。与TIMI评分为3至4分的患者相比（比值比：5.34，95%置信区间：2.64至10.80；p<0.0001），或与TIMI评分为0至2分的患者相比（比值比：29.45，95%置信区间：12.87至67.37；p<0.0001），TIMI评分为5至7分的患者发生三支冠状动脉疾病的可能性更大。与TIMI评分为0至2分的患者相比，TIMI评分为3至4分或5至7分的患者更有可能出现双支冠状动脉疾病（比值比分别为：3.69，95%置信区间：1.60至8.51；p<0.0001和比值比：2.67，95%置信区间：1.04至6.82；p=0.04）。
在UA或NSTEMI后到急诊科就诊的患者中，TIMI评分与受累冠状动脉血管数量之间存在直接且显著的相关性。
