Department of Integrative Medicine and Neurobiology, School of Basic Medical SciencesFudan Institutes of Integrative MedicineState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science Fudan University, Shanghai, China.
Shanghai Key Laboratory of Acupuncture Mechanism and Acupoints, Shanghai, China.
Lasers Med Sci. 2022 Jul;37(5):2343-2352. doi: 10.1007/s10103-022-03540-0. Epub 2022 Apr 11.
Pain is a common symptom of an illness. For decades, pain treatments such as non-steroidal anti-inflammatory drugs, opioids, and surgical nerve blocking have been widely used, but each method has its limitations. Photobiomodulation is a recently developed method for pain management, with light-emitting diodes (LEDs) being a more recent development used in pain management because of their low cost, low side effects, and high safety. Here, we reviewed the phototherapeutic effects of LEDs on different pain conditions. We also discussed possible physicochemical and neurobiological mechanisms underlying LED therapy, especially its effects on inflammatory pain.
疼痛是一种常见的疾病症状。几十年来，非甾体抗炎药、阿片类药物和手术神经阻滞等疼痛治疗方法被广泛应用，但每种方法都有其局限性。光生物调节是一种新开发的疼痛管理方法，发光二极管 (LED) 是一种较新的疼痛管理方法，因为它具有成本低、副作用低和安全性高的特点。在这里，我们回顾了 LED 对不同疼痛情况的光疗效果。我们还讨论了 LED 治疗的可能的物理化学和神经生物学机制，特别是其对炎症性疼痛的影响。
