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新冠肺炎患者的胸背部肌肉量与疾病严重程度有关吗?

Is the Thoracic and Back Muscle Mass Associated with Disease Severity in Patients with COVID-19?

作者信息

Aykın Yığman Zeynep, Karaca Umay Ebru, Aktürk Galip, Ergün Mustafa Çağrı

机构信息

Clinic of Physical Medicine and Rehabilitation, Polatlı Duatepe State Hospital, Ankara, Turkey.

Department of Physical Medicine and Rehabilitation, Health Sciences University, Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey.

出版信息

Turk Thorac J. 2022 Mar;23(2):123-129. doi: 10.5152/TurkThoracJ.2022.21145.

DOI:10.5152/TurkThoracJ.2022.21145
PMID:35404244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9450247/
Abstract

OBJECTIVE

With this study, it was aimed to investigate whether the thoracic muscle mass of patients with coronavirus disease 2019 was related to disease severity and disease characteristics and to evaluate whether muscle mass measurement had a predictive effect on predicting disease severity.

MATERIAL AND METHODS

Two hundred twenty-three subjects (patient group = 161 and control = 62) who presented to our coronavirus disease 2019 outpatient clinic between May 2020 and September 2020 were included in the study. The medication, oxygen, and intubation requirements of the patients and their disease duration and hospital stay were also recorded. At the T4 level, thoracic and back (pectoralis, intercostalis, paraspinals, serratus, and latissimus dorsi) muscles and at the T12 level erector spinae muscles were measured in terms of area (cm2 ).

RESULTS

T4-level muscle cross-sectional area results were found to be negatively correlated with the presence of pneumonia and the requirement of oxygen and intubation. In addition, both T4- and T12-level muscle cross-sectional area results were factors associated with oxygen and intubation requirements. T4-level muscle cross-sectional area results were also associated with the presence of pneumonia.

CONCLUSION

We predict that there may be a relationship between the decrease in the mass of the accessory respiratory muscles and the severity of the disease.

摘要

目的

本研究旨在调查2019冠状病毒病患者的胸部肌肉质量是否与疾病严重程度和疾病特征相关,并评估肌肉质量测量对预测疾病严重程度是否具有预测作用。

材料与方法

本研究纳入了2020年5月至2020年9月期间到我院2019冠状病毒病门诊就诊的223名受试者(患者组=161名,对照组=62名)。记录患者的用药、吸氧和插管需求以及他们的病程和住院时间。在T4水平测量胸部和背部(胸大肌、肋间肌、椎旁肌、锯肌和背阔肌)肌肉,在T12水平测量竖脊肌的面积(cm²)。

结果

发现T4水平的肌肉横截面积结果与肺炎的存在以及吸氧和插管需求呈负相关。此外,T4和T12水平的肌肉横截面积结果都是与吸氧和插管需求相关的因素。T4水平的肌肉横截面积结果也与肺炎的存在有关。

结论

我们预测辅助呼吸肌质量的下降与疾病的严重程度之间可能存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff5/9450247/48d915ceff5a/ttj-23-2-123_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff5/9450247/cb9826cc0a81/ttj-23-2-123_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff5/9450247/48d915ceff5a/ttj-23-2-123_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff5/9450247/cb9826cc0a81/ttj-23-2-123_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff5/9450247/48d915ceff5a/ttj-23-2-123_f002.jpg

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