Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China; School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China.
Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China.
Ultrasonics. 2022 Aug;124:106749. doi: 10.1016/j.ultras.2022.106749. Epub 2022 Apr 8.
The coronavirus Covid-19 mutates quickly in the pandemic, leaves people struggling to verify and improve the effectiveness of the vaccine based on biochemistry. Is there any physical invariant in the variants of such kind of pathogen that could be taken advantage to ease the tensions? To this point, extensive numerical experiments based on continuity mechanics have been accomplished to discover the consistent vibration modes and the range of natural frequency of coronavirus Covid-19. Such invariant could help us in developing some flexible technique to deactivate the coronavirus, like as resonantly breaking the viral spike by ultrasound wave. The fundamental mechanisms governing such process are demonstrated via solving the coupled acoustic wave and elastic dynamic equations, after which the practical strategies are proposed to efficiently realize the technique concept.
在大流行期间,冠状病毒 Covid-19 迅速变异,使得人们难以根据生物化学原理验证和改进疫苗的有效性。在这种病原体的变体中,是否存在任何物理不变量可以被利用来缓解紧张局势?在这一点上,已经完成了基于连续力学的广泛数值实验,以发现冠状病毒 Covid-19 的一致振动模式和固有频率范围。这种不变量可以帮助我们开发一些灵活的技术来使冠状病毒失活,例如通过超声波共振打破病毒的刺突。通过求解耦合的声波和弹性动力学方程,展示了控制这种过程的基本机制,之后提出了有效的实现技术概念的实际策略。