Conceição Aline R, Fraiz Gabriela M, Rocha Daniela M U P, Bressan Josefina
Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Minas Gerais, Brazil.
Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Minas Gerais, Brazil.
Nutr Res. 2022 Jun;102:45-58. doi: 10.1016/j.nutres.2022.03.005. Epub 2022 Mar 14.
The effect of avocado (Persea Americana) on weight loss in people with excess body weight remains unclear. Therefore, we aimed to test our hypothesis that the intake of avocado pulp may be a good strategy for improving anthropometric parameters and, consequently, metabolic health. For this systematic review and meta-analysis, we searched MEDLINE/PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) for studies published between database inception and July 2021. Randomized clinical trials (RCTs) assessing avocado intake on anthropometric parameters (primary outcome) and metabolic parameters (secondary outcomes) were included. Evidence from RCTs were synthesized as differences between standardized mean differences (SMDs) for change in body weight and body composition, comparing the experimental avocado group with control via random-effects meta-analyses. The risk of bias followed the Joanna Briggs Institute Reviewer's Manual. From 781 records identified, 8 studies with 657 individuals were included. No significant changes in body weight, body mass index, percent of body fat, or visceral adipose tissue in response to intervention was seen in the avocado group compared with the control group. Also, the pooled results showed no reduction in body weight and composition (SMD = 0.09; 95% confidence interval, 0.06-0.25; P= .25; I = 0%) of avocado in comparison to control. Secondary outcomes showed some potential benefits in metabolic parameters, mainly related to lipid profile. Regardless, consumption of avocado did not promote weight gain, and further studies are needed to elucidate this effect. The PROSPERO register number of this study is CRD42021266488.
牛油果（鳄梨，Persea Americana）对超重人群体重减轻的影响尚不清楚。因此，我们旨在验证我们的假设，即摄入牛油果果肉可能是改善人体测量参数从而改善代谢健康的良好策略。对于这项系统评价和荟萃分析，我们在MEDLINE/PubMed、EMBASE和Cochrane对照试验中央注册库（CENTRAL）中检索了从数据库建立至2021年7月发表的研究。纳入评估牛油果摄入量对人体测量参数（主要结局）和代谢参数（次要结局）影响的随机临床试验（RCT）。通过随机效应荟萃分析，将试验性牛油果组与对照组进行比较，以标准化均数差值（SMD）的差异形式综合RCT的证据，这些差值用于衡量体重和身体成分的变化。偏倚风险遵循乔安娜·布里格斯研究所评审手册。从识别出的781条记录中，纳入了8项研究，共657名个体。与对照组相比，牛油果组在干预后体重、体重指数、体脂百分比或内脏脂肪组织方面未见显著变化。此外，汇总结果显示，与对照组相比，牛油果对体重和身体成分无降低作用（SMD = 0.09；95%置信区间，0.06 - 0.25；P = 0.25；I² = 0%）。次要结局显示，在代谢参数方面有一些潜在益处，主要与血脂谱有关。无论如何，食用牛油果不会导致体重增加，需要进一步研究来阐明这种影响。本研究在国际前瞻性系统评价注册库（PROSPERO）的注册号为CRD42021266488。
