CICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal.
Departamento da Saúde da Criança e da Mulher, Centro Hospitalar Universitário Cova da Beira, 6200-251 Covilhã, Portugal.
Nutrients. 2022 Mar 27;14(7):1393. doi: 10.3390/nu14071393.
Iodine deficiency is a common problem in pregnant women and may have implications for maternal and child health. Iodine supplementation during pregnancy has been recommended by several scientific societies. We undertook a cross-sectional survey to assess the efficacy of these recommendations in a European iodine-deficient region. Urinary iodine concentrations (UIC) were determined in pregnant women before (n = 203) and after (n = 136) the implementation of guidelines for iodine supplementation in pregnancy. Iodine supplementation (200 μg/day) reduced the proportion of pregnant women with severe iodine deficiency (37.4% to 18.0%, p = 0.0002). The median UIC increased from 67.6 µg/L to 106.8 µg/L but remained below the recommended target level (>150 µg/L) for pregnant women. In conclusion, iodine supplementation in pregnant women improved iodine status in this iodine-deficient region but was insufficient to achieve recommended iodine levels in pregnancy. Additional measures, such as the adjustment of the dose or timing of supplementation, or universal salt iodization, may be needed.
碘缺乏是孕妇中常见的问题，可能对母婴健康产生影响。一些科学协会建议在怀孕期间补充碘。我们进行了一项横断面调查，以评估这些建议在欧洲碘缺乏地区的效果。在实施孕期碘补充指南之前（n=203）和之后（n=136），我们测定了孕妇的尿碘浓度（UIC）。碘补充（200μg/天）降低了严重碘缺乏孕妇的比例（从 37.4%降至 18.0%，p=0.0002）。UIC 中位数从 67.6μg/L 增加到 106.8μg/L，但仍低于推荐的孕妇目标水平（>150μg/L）。总之，孕妇补充碘可改善碘缺乏地区的碘营养状况，但仍不足以达到孕期推荐的碘水平。可能需要采取其他措施，如调整剂量或补充时间，或实施全民食盐碘化。
