Pires Laura S, Magalhães Fernão D, Pinto Artur M
LEPABE, Faculdade de Engenharia, Universidade do Porto, Rua Roberto Frias, 4200-465 Porto, Portugal.
i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 4200-135 Porto, Portugal.
Polymers (Basel). 2022 Apr 4;14(7):1464. doi: 10.3390/polym14071464.
The constant evolution and advancement of the biomedical field requires robust and innovative research. Two-dimensional nanomaterials are an emerging class of materials that have risen the attention of the scientific community. Their unique properties, such as high surface-to-volume ratio, easy functionalization, photothermal conversion, among others, make them highly versatile for a plethora of applications ranging from energy storage, optoelectronics, to biomedical applications. Recent works have proven the efficiency of 2D nanomaterials for cancer photothermal therapy (PTT), drug delivery, tissue engineering, and biosensing. Combining these materials with hydrogels and scaffolds can enhance their biocompatibility and improve treatment for a variety of diseases/injuries. However, given that the use of two-dimensional nanomaterials-based polymeric composites for biomedical applications is a very recent subject, there is a lot of scattered information. Hence, this review gathers the most recent works employing these polymeric composites for biomedical applications, providing the reader with a general overview of their potential.
生物医学领域的不断发展和进步需要强大而创新的研究。二维纳米材料是一类新兴材料,已引起科学界的关注。它们具有独特的性质,如高比表面积、易于功能化、光热转换等,使其在从能量存储、光电子学到生物医学应用等众多领域具有高度的通用性。最近的研究已经证明了二维纳米材料在癌症光热疗法(PTT)、药物递送、组织工程和生物传感方面的有效性。将这些材料与水凝胶和支架相结合可以提高其生物相容性,并改善对各种疾病/损伤的治疗。然而,鉴于基于二维纳米材料的聚合物复合材料在生物医学应用中的使用是一个非常新的课题,目前存在很多分散的信息。因此,本综述收集了使用这些聚合物复合材料进行生物医学应用的最新研究成果,为读者提供其潜力的总体概述。