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探索西巴尔干山脉生物活性酚类化合物的新来源。

Exploring New Sources of Bioactive Phenolic Compounds from Western Balkan Mountains.

作者信息

Karalija Erna, Dahija Sabina, Demir Arnela, Bešta-Gajević Renata, Zeljković Sanja Ćavar, Tarkowski Petr

机构信息

Laboratory for Plant Physiology, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosnia and Herzegovina.

Laboratory for Microbiology, Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosnia and Herzegovina.

出版信息

Plants (Basel). 2022 Apr 6;11(7):1002. doi: 10.3390/plants11071002.

DOI:10.3390/plants11071002
PMID:35406980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9002936/
Abstract

This study presents the first report on phenolic composition and bioactivity of ethanolic extracts of three plant species that grow in the western Balkan mountains and are used in traditional folk medicine: , , and . Phenolics were extracted from different aerial plant parts using 80% ethanol to assess the possibility of sustainable use of these plants as a source of bioactive compounds without disruption to the roots (for ) or destruction of whole habitats (for and ). The ethanolic extract of flower contained noticeable levels of apigenin and quercetin. The branches and bark of were significantly rich in catechin, while rutin was the major phenolic found in the leaf extract of . Furthermore, the flower extract of revealed the best antioxidant activity, which was comparable to 4-hydroxybenzoic acid and quercetin. Considering antimicrobial activity, the leaf extracts of and demonstrated potent activity against all microbes tested, while the extracts of were moderately effective. The presented results emphasize the potential of these plants as novel sources of bioactive compounds.

摘要

本研究首次报道了生长在巴尔干山脉西部且用于传统民间医学的三种植物乙醇提取物的酚类成分和生物活性

[植物名称1]、[植物名称2]和[植物名称3]。使用80%乙醇从植物不同地上部分提取酚类物质,以评估在不破坏根部(对于[植物名称1])或整个栖息地(对于[植物名称2]和[植物名称3])的情况下,可持续利用这些植物作为生物活性化合物来源的可能性。[植物名称1]花的乙醇提取物含有显著水平的芹菜素和槲皮素。[植物名称2]的树枝和树皮富含儿茶素,而芦丁是[植物名称3]叶提取物中主要的酚类物质。此外,[植物名称1]的花提取物表现出最佳的抗氧化活性,与4 - 羟基苯甲酸和槲皮素相当。考虑到抗菌活性,[植物名称2]和[植物名称3]的叶提取物对所有测试微生物均表现出强效活性,而[植物名称1]的提取物效果中等。所呈现的结果强调了这些植物作为生物活性化合物新来源的潜力。

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本文引用的文献

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Biology (Basel). 2021 Jul 2;10(7):612. doi: 10.3390/biology10070612.
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Phenolic Compounds and Biological Activity of Selected Species.选定物种的酚类化合物与生物活性
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A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective.
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Campanula macrostachya: biological activity and identification of phenolics using a liquid chromatography electrospray ionization tandem mass spectrometry system.大钟花:生物活性及酚类物质的液质联用鉴定
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Plant Phenolics: Bioavailability as a Key Determinant of Their Potential Health-Promoting Applications.植物酚类化合物:生物利用度作为其潜在健康促进应用的关键决定因素。
Antioxidants (Basel). 2020 Dec 12;9(12):1263. doi: 10.3390/antiox9121263.
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