前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描在肾细胞癌中的应用：当前文献综述
PSMA PET/CT in Renal Cell Carcinoma: An Overview of Current Literature.
作者信息
Muselaers Stijn, Erdem Selcuk, Bertolo Riccardo, Ingels Alexandre, Kara Önder, Pavan Nicola, Roussel Eduard, Pecoraro Angela, Marchioni Michele, Carbonara Umberto, Marandino Laura, Amparore Daniele, Campi Riccardo
机构信息
Department of Urology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Division of Urologic Oncology, Department of Urology, Faculty of Medicine, Istanbul University, Istanbul 34452, Turkey.
出版信息
J Clin Med. 2022 Mar 25;11(7):1829. doi: 10.3390/jcm11071829.
Abstract
Although the vast majority of prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging occurs in the field of prostate cancer, PSMA is also highly expressed on the cell surface of the microvasculature of several other solid tumors, including renal cell carcinoma (RCC). This makes it a potentially interesting imaging target for the staging and monitoring of RCC. The objective of this review is to provide an overview of the current evidence regarding the use of PSMA PET/Computed Tomography in RCC patients.
摘要
尽管绝大多数前列腺特异性膜抗原（PSMA）正电子发射断层扫描（PET）成像应用于前列腺癌领域，但PSMA在包括肾细胞癌（RCC）在内的其他几种实体瘤的微血管细胞表面也高度表达。这使其成为RCC分期和监测的一个潜在有趣的成像靶点。本综述的目的是概述目前关于PSMA PET/计算机断层扫描在RCC患者中应用的证据。
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