Riotto Eleonora, Mégevand Vladimir, Mégevand Alexis, Marti Christophe, Pugin Jerome, Stangos Alexandros N, Marconi Archinto Leonardo, Sunaric Mégevand Gordana
Faculty of Medicine, University Hospital Geneva, 1205 Geneva, Switzerland.
Department of Surgery, University Hospital Geneva, 1205 Geneva, Switzerland.
J Clin Med. 2022 Mar 25;11(7):1828. doi: 10.3390/jcm11071828.
The recent outbreak of the Coronavirus SARS-CoV-2 has been declared a worldwide pandemic. Within various multi-organ involvement, several ocular manifestations have been described, such as conjunctivitis and retinopathy. The prevalence and severity of retinal lesions and their relation to the severity of the systemic disease are unknown. We performed a prospective, observational study on 172 consecutively hospitalized patients with acute confirmed COVID-19 infection. All patients underwent screening widefield fundus photography at the time of hospital admission. Despite no ocular or vision-related symptoms, we found cotton wool spots (CWS) and/or hemorrhages in 19/172 patients (11%). Diabetes history, overweight, and elevated C-reactive protein were more frequently observed among patients with retinal abnormalities, while a history of systemic hypertension was more frequently observed among patients without retinal findings. At a 3-month follow-up visit, CWS had subsided in all patients.
最近新型冠状病毒SARS-CoV-2的爆发已被宣布为全球大流行。在各种多器官受累情况中，已经描述了几种眼部表现，如结膜炎和视网膜病变。视网膜病变的患病率和严重程度及其与全身疾病严重程度的关系尚不清楚。我们对172例连续住院的急性确诊COVID-19感染患者进行了一项前瞻性观察研究。所有患者在入院时均接受了广角眼底照相筛查。尽管没有眼部或视力相关症状，但我们在19/172例患者（11%）中发现了棉絮斑（CWS）和/或出血。视网膜异常患者中糖尿病史、超重和C反应蛋白升高更为常见，而无视网膜病变的患者中系统性高血压病史更为常见。在3个月的随访中，所有患者的棉絮斑均已消退。
