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解脲脲原体血清型(血清变种)之间的遗传相关性。

Genetic relatedness among Ureaplasma urealyticum serotypes (serovars).

作者信息

Razin S, Yogev D

出版信息

Pediatr Infect Dis. 1986 Nov-Dec;5(6 Suppl):S300-4. doi: 10.1097/00006454-198611010-00022.

DOI:10.1097/00006454-198611010-00022
PMID:3540904
Abstract

Fourteen serotypes (serovars) are currently recognized in the species Ureaplasma urealyticum. DNA-DNA hybridization tests, cleavage of genomic DNA by restriction endonucleases, and polyacrylamide gel electrophoresis of cell proteins indicate that the U. urealyticum serotypes fall into two genotypically distinct, but related, clusters. Southern hybridization tests of mycoplasmal ribosomal RNA gene probes with DNAs of the various serotypes digested by restriction endonucleases showed that the U. urealyticum chromosome carries two sets (operons) of ribosomal RNA genes. However, the hybridization patterns produced by the serotypes showed differences which were most pronounced among serotypes belonging to the two different clusters.

摘要

目前在解脲脲原体物种中已识别出14种血清型(血清变种)。DNA - DNA杂交试验、用限制性内切酶切割基因组DNA以及细胞蛋白的聚丙烯酰胺凝胶电泳表明,解脲脲原体血清型可分为两个基因型不同但相关的簇。用限制性内切酶消化的各种血清型DNA与支原体核糖体RNA基因探针进行的Southern杂交试验表明,解脲脲原体染色体携带两组(操纵子)核糖体RNA基因。然而,血清型产生的杂交模式显示出差异,在属于两个不同簇的血清型之间差异最为明显。

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1
Genetic relatedness among Ureaplasma urealyticum serotypes (serovars).解脲脲原体血清型(血清变种)之间的遗传相关性。
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引用本文的文献

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BMC Infect Dis. 2024 Oct 28;24(1):1213. doi: 10.1186/s12879-024-10113-9.
2
Phylogeny-based rapid identification of mycoplasmas and ureaplasmas from urethritis patients.基于系统发育学从尿道炎患者中快速鉴定支原体和脲原体。
J Clin Microbiol. 2002 Jan;40(1):105-10. doi: 10.1128/JCM.40.1.105-110.2002.
3
Development of an enzyme-linked immunosorbent assay for serotyping ureaplasma urealyticum strains using monoclonal antibodies.
利用单克隆抗体开发用于解脲脲原体菌株血清分型的酶联免疫吸附测定法。
Clin Diagn Lab Immunol. 2001 Jan;8(1):52-7. doi: 10.1128/CDLI.8.1.52-57.2001.
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Development of monoclonal antibodies against Ureaplasma urealyticum serotypes and their use for serotyping clinical isolates.抗解脲脲原体血清型单克隆抗体的研制及其在临床分离株血清分型中的应用。
Clin Diagn Lab Immunol. 2000 Jul;7(4):563-7. doi: 10.1128/CDLI.7.4.563-567.2000.
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Ureaplasma urealyticum intrauterine infection: role in prematurity and disease in newborns.解脲脲原体宫内感染:在早产和新生儿疾病中的作用
Clin Microbiol Rev. 1993 Jan;6(1):69-87. doi: 10.1128/CMR.6.1.69.
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