每日两次服用枸橼酸铋钾治疗十二指肠溃疡。
Twice daily tripotassium dicitrato bismuthate in the treatment of duodenal ulceration.
作者信息
Hollanders D
出版信息
Postgrad Med J. 1986 Jan;62(723):19-21. doi: 10.1136/pgmj.62.723.19.
Abstract
Fifty three patients with endoscopically proven duodenal ulceration have cooperated in a clinical trial to compare the ulcer healing effect of tripotassium dicitrato bismuthate (TDB) at standard dosage administered either twice or four times daily. No statistically significant difference has been found to exist between ulcer healing in the two groups at 4 weeks (72% and 67%, P = 0.944) or at 8 weeks (92% and 81%, P = 0.504) and it is concluded that twice daily TDB maintains the effectiveness of the drug and has advantages for patient compliance.
摘要
五十三例经内镜证实为十二指肠溃疡的患者参与了一项临床试验，以比较每日服用两次或四次标准剂量的枸橼酸铋钾（TDB）的溃疡愈合效果。在4周时（72%和67%，P = 0.944）或8周时（92%和81%，P = 0.504），两组的溃疡愈合情况均未发现统计学上的显著差异，得出的结论是，每日两次服用TDB可维持药物疗效，且对患者的依从性有好处。
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