Key Laboratory of Public Health Safety, NHC Key Laboratory of Health Technology Assessment, Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China.
Guizhou Province Centre for Disease Control and Prevention, 101 Bageyan Road, Yunyan District, Guiyang 550004, China.
Int J Environ Res Public Health. 2022 Mar 23;19(7):3801. doi: 10.3390/ijerph19073801.
Based on a prospective cohort study of adults from southwest China with heterogeneity in their demographical characteristics and lifestyles, we aimed to explore the association between drinking patterns and incident hypertension under the interaction of these confounding factors. The Cox proportional hazard model was used to estimate the hazard ratios (HR) and 95% confidence intervals (95% CI). Subgroup analysis was performed according to sex, ethnicity, area, occupation, smoking, and exercise to compare the differences in the association between drinking patterns and the incidence of hypertension. Blood pressure was higher in participants with a high drinking frequency than those with a low drinking frequency (p < 0.001). We found that total drinking frequency, liquor drinking frequency, rice wine drinking frequency, and alcohol consumption were significantly associated with an increased risk of hypertension. Compared with the non-drinking group, a heavy drinking pattern was positively correlated with hypertension. Drinking can increase the risk of hypertension, especially heavy drinking patterns, with a high frequency of alcohol intake and high alcohol consumption. From the analysis results of the longitudinal data, drinking alcohol is still an important risk factor for hypertension among Chinese subjects, especially for men, the rural population, the employed, the Han nationality, smokers, and certain exercise populations.
基于一项对中国西南部成年人的前瞻性队列研究,这些成年人在人口统计学特征和生活方式方面存在异质性,我们旨在探讨在这些混杂因素的相互作用下,饮酒模式与高血压事件之间的关联。Cox 比例风险模型用于估计风险比(HR)和 95%置信区间(95%CI)。根据性别、种族、地区、职业、吸烟和运动进行亚组分析,比较不同饮酒模式与高血压发病率之间关联的差异。高饮酒频率组的参与者血压高于低饮酒频率组(p<0.001)。我们发现总饮酒频率、白酒饮酒频率、米酒饮酒频率和酒精摄入量与高血压风险增加显著相关。与非饮酒组相比,重度饮酒模式与高血压呈正相关。饮酒会增加患高血压的风险,尤其是重度饮酒模式,与饮酒频率高和酒精摄入量高有关。从纵向数据分析结果来看,饮酒仍然是中国人群患高血压的一个重要危险因素,尤其是男性、农村人口、就业人群、汉族、吸烟者和某些运动人群。