School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Cardiovascular Medicine, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
BMC Public Health. 2021 Nov 9;21(1):2053. doi: 10.1186/s12889-021-12140-6.
We investigated the association of alcohol consumption with cardiovascular and non-cardiovascular mortality in elderly Chinese men.
Our participants were recruited from residents living in a suburban town of Shanghai (≥60 years of age, n = 1702). Alcohol intake was classified as non-drinkers, past drinkers (stopped drinking for ≥12 months), and current light-to-moderate (1 to 299 g/week) and heavy drinkers (≥300 g/week). Alcoholic beverages were classified as beer/wine, rice aperitif and liquor/mix drinking.
During 5.9 years (median) of follow-up, all-cause, cardiovascular and non-cardiovascular deaths occurred in 211, 98 and 113 participants, respectively. The corresponding incidence rates were 23.6/1000, 10.9/1000 and 12.6/1000 person-years, respectively. Both before and after adjustment for confounding factors, compared with non-drinkers (n = 843), past drinkers (n = 241), but not the current light-to-moderate (n = 241) or heavy drinkers (n = 377), had a higher risk of all-cause (adjusted hazard ratio [HR] 1.90, 95% confidence interval [CI] 1.35-2.68, P = 0.0003) and non-cardiovascular mortality (HR 2.46, 95% CI 1.55-3.91, P = 0.0001). Similar trends were observed for cardiovascular mortality (HR 1.44, 95% CI 0.85-2.44, P = 0.18). In similar unadjusted and adjusted analyses, compared with the current beer/wine drinkers (n = 203), liquor/mix drinkers (n = 142), but not aperitif drinkers (n = 273), had a significantly higher risk of all-cause (HR 3.07, 95% CI 1.39-6.79, P = 0.006), and cardiovascular mortality (HR 10.49, 95% CI 2.00-55.22, P = 0.006). Similar trends were observed for non-cardiovascular mortality (HR 1.94, 95% CI 0.73-5.16, P = 0.18).
Our study showed risks of mortality associated with past drinking and liquor drinking in the elderly Chinese men.
我们研究了饮酒与老年中国男性心血管和非心血管死亡率的关系。
我们的参与者来自上海郊区一个城镇的居民（年龄≥60 岁，n=1702）。饮酒情况分为不饮酒者、既往饮酒者（停止饮酒≥12 个月）、目前轻至中度饮酒者（每周 1 至 299 克）和重度饮酒者（每周≥300 克）。酒精饮料分为啤酒/葡萄酒、米酒开胃酒和白酒/混合酒。
在 5.9 年（中位数）的随访期间，所有原因、心血管和非心血管死亡分别发生在 211、98 和 113 名参与者中，相应的发病率分别为 23.6/1000、10.9/1000 和 12.6/1000 人年。在调整混杂因素前后，与不饮酒者（n=843）相比，既往饮酒者（n=241）而非目前轻至中度饮酒者（n=241）或重度饮酒者（n=377），全因死亡率（调整后的危险比 [HR] 1.90，95%置信区间 [CI] 1.35-2.68，P=0.0003）和非心血管死亡率（HR 2.46，95%CI 1.55-3.91，P=0.0001）均较高。心血管死亡率也有类似趋势（HR 1.44，95%CI 0.85-2.44，P=0.18）。在类似的未调整和调整分析中，与目前饮用啤酒/葡萄酒者（n=203）相比，饮用白酒/混合酒者（n=142）而非饮用米酒开胃酒者（n=273）的全因死亡率（HR 3.07，95%CI 1.39-6.79，P=0.006）和心血管死亡率（HR 10.49，95%CI 2.00-55.22，P=0.006）均显著升高。非心血管死亡率也有类似趋势（HR 1.94，95%CI 0.73-5.16，P=0.18）。
本研究表明，在老年中国男性中，既往饮酒和白酒饮酒与死亡风险相关。
