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饮酒发生率、风险因素和行为改变:来自中国西南部社区为基础队列研究的结果。

Incidence rate, risk factors and behaviour changes for alcohol drinking: findings from a community-based cohort study in Southwest China.

机构信息

NHC Key Laboratory of Health Technology Assessment, Fudan University School of Public Health, Shanghai, China.

Institute of Chronic Disease Control, Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province, China.

出版信息

BMJ Open. 2022 Sep 13;12(9):e060914. doi: 10.1136/bmjopen-2022-060914.

Abstract

OBJECTIVE

To describe changes in alcohol drinking behaviour, estimate the incidence rate of alcohol drinking and explore its risk factors in the Chinese community population.

DESIGN

A community population prospective cohort study.

SETTING

A total of 48 townships of 12 counties or districts in Guizhou province, China.

PARTICIPANTS

With the multistage proportional stratified cluster sampling method, a total of 7343 adult residents were enrolled into this study and eligible to be analysed.

PRIMARY AND SECONDARY OUTCOME MEASURES

The incidence rate and its risk factor (adjusted HR (aHR) and 95% CIs) as well as the prevalence of alcohol drinking.

RESULTS

There was a little increase trend in the overall prevalence of alcohol drinking among 7343 subjects over an average of 7.22-year follow-up, and the prevalence in women increased by 2.5% statistically (p=0.001). Among 5005 non-drinkers in 7343 subjects at baseline, 1107 incident drinkers were identified, and the incidence rate of alcohol drinking was estimated at 30.63/1000 person-years with significant sex difference (57.46 vs 17.99 per 1000 person-years for men and women, respectively, p<0.001). The incidence rate decreased gradually with age, peaking in men aged 18-29 years old and women aged 30-39 years old at baseline. After the adjustment for covariates, being male (aHR=3.46, 95% CI: 3.02 to 3.96), being non-Han Chinese (aHR=1.65, 95% CI: 1.44 to 1.88), living in urban areas (aHR=3.50, 95% CI: 3.01 to 4.08), being employed (aHR=1.33, 95% CI: 1.16 to 1.52), smoking (aHR=1.17, 95% CI: 1.00 to 1.38) and having no history of chronic diseases (aHR=1.19, 95% CI: 1.04 to 1.35) were independent risk factors for incident drinkers.

CONCLUSION

The number of women increased in the prevalence of alcohol drinking significantly although there was no significant overall change for the cohort population in Southwest China. Also, there was a high risk of developing alcohol drinking among the study population, especially for those non-drinkers who were younger men, non-Han Chinese, living in urban areas, employed, current smokers or without any chronic diseases. Interventions to prevent and manage alcohol consumption should be designed and implemented in Chinese communities as soon as possible.

摘要

目的

描述饮酒行为的变化,估计饮酒的发生率,并探讨其在中国社区人群中的危险因素。

设计

一项社区人群前瞻性队列研究。

地点

中国贵州省 12 个县或区的 48 个乡镇。

参与者

采用多阶段比例分层聚类抽样方法,共纳入 7343 名成年居民进行分析。

主要和次要结局测量

发生率及其危险因素(调整后的 HR(aHR)和 95%置信区间)以及饮酒的流行率。

结果

在平均 7.22 年的随访中,7343 名受试者的总体饮酒流行率呈略有上升趋势,女性的饮酒流行率统计学上增加了 2.5%(p=0.001)。在基线时的 7343 名非饮酒者中,有 1107 名新饮酒者,饮酒发生率估计为 30.63/1000 人年,性别差异显著(男性为 57.46/1000 人年,女性为 17.99/1000 人年,p<0.001)。发生率随年龄逐渐下降,在男性 18-29 岁和女性 30-39 岁时达到峰值。在调整了协变量后,男性(aHR=3.46,95%CI:3.02 至 3.96)、非汉族(aHR=1.65,95%CI:1.44 至 1.88)、居住在城市地区(aHR=3.50,95%CI:3.01 至 4.08)、就业(aHR=1.33,95%CI:1.16 至 1.52)、吸烟(aHR=1.17,95%CI:1.00 至 1.38)和无慢性病史(aHR=1.19,95%CI:1.04 至 1.35)是新饮酒者的独立危险因素。

结论

尽管西南地区队列人群总体饮酒流行率无显著变化,但女性饮酒流行率显著增加。此外,该研究人群饮酒风险较高,尤其是那些年轻男性、非汉族、居住在城市地区、就业、当前吸烟者或无任何慢性疾病的非饮酒者。应尽快在中国社区设计和实施预防和管理饮酒的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf9/9472170/41ce0597b355/bmjopen-2022-060914f01.jpg

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