Department of Environmental Engineering, College of Environment, Sichuan Agricultural University, Chengdu 611100, China.
Int J Environ Res Public Health. 2022 Apr 2;19(7):4245. doi: 10.3390/ijerph19074245.
Bisphenol A (BPA) is an important industrial chemical; bisphenol S (BPS) is a substitute for BPA. Both are frequently detected in rivers, sewage, and surface water, and have a great impact on the water environment. The effects of BPA and BPS on cell growth, chlorophyll a content, and oxidative stress of () were studied. When BPA and BPS acted alone or in combination, compared with the blank control group, the growth of in the experimental group showed a pattern of "low promotion and high inhibition", and the inhibition rate reached the maximum on the 6th day. Under the combined action, the reactive oxygen species (ROS) level of first increased, and then decreased. In addition, the activity of superoxide dismutase (SOD) and peroxidase (POD) increased with the increase in combined concentration. In the 0.5 P treatment group, SOD and POD activity reached peak values of 29.59 U/mg∙prot and 1.35 U/mg∙prot, respectively. The combined toxicity of BPA and BPS to was evaluated as a synergistic effect by using toxicity unit and additive index methods. This study evaluated the effects of BPA and BPS on algae in the aquatic environment, providing some data support for their potential ecological risks.
双酚 A（BPA）是一种重要的工业化学品；双酚 S（BPS）是 BPA 的替代品。两者都经常在河流、污水和地表水，对水环境有很大的影响。本研究探讨了 BPA 和 BPS 对（）细胞生长、叶绿素 a 含量和氧化应激的影响。当 BPA 和 BPS 单独或联合作用时，与空白对照组相比，实验组的生长呈现“低促进高抑制”的模式，第 6 天抑制率达到最大值。在联合作用下，（）的活性氧（ROS）水平先升高后降低。此外，超氧化物歧化酶（SOD）和过氧化物酶（POD）的活性随着联合浓度的增加而增加。在 0.5 P 处理组中，SOD 和 POD 的活性分别达到 29.59 U/mg·prot 和 1.35 U/mg·prot 的峰值。本研究采用毒性单位和加性指数法评价了 BPA 和 BPS 对藻类的联合毒性，为其潜在生态风险提供了一定的数据支持。本研究评估了 BPA 和 BPS 对水生环境中藻类的影响，为其潜在生态风险提供了一定的数据支持。
