Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, 20-090 Lublin, Poland.
Laboratory of Radiometric Expertise, Institute of Nuclear Physics PAN, 31-342 Cracow, Poland.
Int J Environ Res Public Health. 2022 Apr 2;19(7):4257. doi: 10.3390/ijerph19074257.
Exposure to radon is the second most common factor causing lung cancer in smokers and the first among non-smokers. We aimed to measure the impact of the radon exposure on patients with different histological types of advanced lung cancer. The measurement of radon exposure was performed in 102 patients with lung cancer in stage 3B or higher (Poland). There were 78.4% of patients with non-small cell carcinoma and 21.6% of patients with small cell carcinoma. One month radon exposure measurement was performed with trace detectors in order to control whether high radon concentrations (>800 Bq/m3) were found in the homes of patients with cancer diagnosed. Results of the determinations were then compared with the representation of the most common types of lung cancer in the study population. In the analyzed group, the average concentration of radon during the exposure of the detector in the residential premises of the respondents accounted for 69.0 Bq/m3 [37.0−117.0] and had no statistically significant effect on the type of lung cancer developed in patients. The lack of statistical significance may result from the small study group and the accompanying exposure to other harmful components. As the incidence of lung adenocarcinoma is increasing and exposure to tobacco smoke is decreasing, the search for other modifiable causes of lung cancer should be the task in the future.
氡暴露是导致吸烟者肺癌的第二大常见因素，也是非吸烟者肺癌的首要因素。我们旨在测量氡暴露对不同组织学类型晚期肺癌患者的影响。在波兰，对 102 名处于 3B 期或更高阶段的肺癌患者进行了氡暴露测量。其中 78.4%的患者是非小细胞癌，21.6%的患者是小细胞癌。使用微量探测器进行了一个月的氡暴露测量，以控制是否在诊断患有癌症的患者家中发现高氡浓度（>800 Bq/m3）。然后将测定结果与研究人群中最常见的肺癌类型的代表性进行比较。在分析组中，在受访者住宅场所中探测器暴露期间氡的平均浓度为 69.0 Bq/m3 [37.0-117.0]，对患者中发生的肺癌类型没有统计学显著影响。缺乏统计学意义可能是由于研究小组规模较小，以及伴随的其他有害成分的暴露。由于肺腺癌的发病率不断上升，且吸烟暴露减少，因此寻找其他可改变的肺癌病因应该是未来的任务。
