Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kerava Health Care Center, Kerava, Finland.
Nord J Psychiatry. 2023 Jan;77(1):65-72. doi: 10.1080/08039488.2022.2061047. Epub 2022 Apr 12.
Major public and scientific interest exists on, whether quarantine as a containment measure, could have adverse effects on individual's mental health. We investigated psychic well-being and distress, symptoms of depression and anxiety among individuals imposed to home quarantine.
By total population sampling in a Finnish suburban city, a total of 57 quarantined cases (participation rate 97%) were identified and followed up for two weeks until expiration of the quarantine. A randomized control group ( = 53) was formed of people seeking laboratory testing for suspected Sars-CoV-2 infection. Primary outcome was the psychic well-being and distress experienced during quarantine measured by the Clinical Outcomes in Routine Evaluation - Outcome Measure (CORE-OM). The cases were followed up by the Clinical Outcomes in Routine Evaluation-10 (CORE-10), Patient Health Questionnaire-9 (PHQ-9), and by the Overall Anxiety Severity and Impairment Scale (OASIS).
The median CORE-OM score for the cases was 3.53 (95% CI: 2.23-4.66), and for the controls 3.24 (1.76-3.82), being mostly in the nonclinical to mild range. The difference between the groups was statistically nonsignificant ( = .19). Higher levels of psychic distress were explained by previous psychiatric disorders and living alone, but not having been quarantined. In comparison to controls, the quarantined participants experienced significantly, but slightly lower level of life functioning. At the follow-up, the quarantined participants rated further low on the CORE-10 (median 2.00; 95% CI: 1.00-3.00), the PHQ-9 (1.50; 0.00-3.00), and the OASIS (0.00; 0.00-0.00).
The distress associated with short-term home quarantine may not be to the degree of a mental disorder.
公众和科学界都非常关注隔离作为一种控制措施,是否会对个人的心理健康产生不良影响。我们调查了被强制居家隔离的个体的心理幸福感和困扰、抑郁和焦虑症状。
通过在芬兰郊区城市进行总人口抽样,共确定了 57 例被隔离的病例(参与率为 97%),并对他们进行了为期两周的随访,直至隔离结束。选择因疑似 SARS-CoV-2 感染而寻求实验室检测的 53 人作为随机对照组。主要结局是通过临床结果在常规评估-结局测量(CORE-OM)评估隔离期间的心理幸福感和困扰。通过临床结果在常规评估-10(CORE-10)、患者健康问卷-9(PHQ-9)和总体焦虑严重程度和障碍量表(OASIS)对病例进行随访。
病例组的 CORE-OM 评分中位数为 3.53(95%CI:2.23-4.66),对照组为 3.24(1.76-3.82),主要处于非临床到轻度范围。两组间差异无统计学意义( = .19)。较高的心理困扰程度可由先前的精神障碍和独居解释,但与隔离无关。与对照组相比,被隔离的参与者的生活功能明显较低,但略低。在随访时,被隔离的参与者的 CORE-10(中位数 2.00;95%CI:1.00-3.00)、PHQ-9(1.50;0.00-3.00)和 OASIS(0.00;0.00-0.00)评分进一步降低。
短期居家隔离引起的困扰可能尚未达到精神障碍的程度。