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Acute confusional migraine in CADASIL: A case report and literature review.

作者信息

Ferrante Enrico, Trimboli Michele, Erminio Cristina, Martino Iolanda, Tiraboschi Pietro

机构信息

Department of Neurology, Alto Vicentino Hospital - AULSS 7 Pedemontana, Santorso (IT), Italy; Department of Neurology, AOR San Carlo, Potenza, Italy; Department of Neuroradiology, Niguarda Ca Granda Hospital-Milan (IT), Italy.

Department of Neurology, AOR San Carlo, Potenza, Italy; Institute of Neurology, Department of Medical and Surgical Sciences, Magna Græcia University, Catanzaro (IT), Italy.

出版信息

Clin Neurol Neurosurg. 2022 May;216:107239. doi: 10.1016/j.clineuro.2022.107239. Epub 2022 Apr 6.

Abstract

BACKGROUND

Acute confusional state associated with migraine in adults is an infrequent entity. Around 30-60% of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients get affected by migraine attacks-the majority with aura-often as the first symptom of the disease. Acute confusional state during migraine has been rarely described in CADASIL patients and a complete neuropsychological assessment during the acute phase has never been conducted so far.

CASE SUMMARY

We here describe the clinical and neuropsychological features of two distinct episodes of ACM in a 54-year-old female with CADASIL. EEG recording during acute confusional migraine and after attack resolution and neuroimaging has been reported.

DISCUSSION AND LITERATURE REVIEW

This paper also reports a literature review on the topic of ACM in CADASIL highlighting a lack of adequate knowledge about this entity among clinicians and prompting further larger studies to explore its incidence and characteristics.

摘要

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