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基于智能算法的胃肠道 X 射线检查评估益生菌联合三联疗法对 感染患儿的治疗效果。

Intelligent Algorithm-Based Gastrointestinal X-Ray Examination in Evaluating the Therapeutic Effect of Probiotics Combined with Triple Therapy on Children with Infection.

机构信息

Department of Pediatrics, Huai'an Maternal and Child Health Care Hospital, Huai'an 223002, Jiangsu, China.

出版信息

Contrast Media Mol Imaging. 2022 Mar 27;2022:8464361. doi: 10.1155/2022/8464361. eCollection 2022.

Abstract

In this study, gastrointestinal X-ray imaging was processed based on the Ncut algorithm, the gastric signs of the children after probiotics combined with triple therapy were examined, the therapeutic effect of probiotics combined with triple therapy was evaluated, and the correlation between (HP) infection and gastric disease was analyzed. The included children were randomly divided into group A (treated with standard triple therapy) and group B (pretreated with probiotics on the basis of the treatment method of group A) with 48 cases in each group. The gastrointestinal angiography results of children were observed. The accuracy of the gastrointestinal angiography based on intelligent algorithms was evaluated by taking the results of the urea breath test (UBT) as the gold standard. The results were as follows: first, gastrointestinal X-ray imaging before and after treatment showed that the recovery of the gastric body and gastric antral mucosa for children in group B was better than that of group A ( < 0.05); second, the incidence of gastrointestinal diseases in HP-positive patients was 78% and the incidence of HP-negative patients was 32%; third, the sensitivity, specificity, and accuracy of gastrointestinal X-ray imaging based on intelligent algorithm were 76.47%, 93.67%, and 90.63%, respectively. After treatment, tumor necrosis factor (TNF-) and interleukin 6 (IL-6) in group B were much lower than those in group A ( < 0.05), and the incidence of adverse reactions in group B was lower than that in group A ( < 0.05). In summary, gastrointestinal X-ray imaging based on intelligent algorithm had a reliable reference value for the judgment of gastrointestinal HP infection and probiotics combined with triple therapy was more effective for HP infection, which was worthy of clinical application.

摘要

在这项研究中,基于 Ncut 算法对胃肠道 X 射线成像进行处理,检查了益生菌联合三联疗法后儿童的胃征象,评估了益生菌联合三联疗法的治疗效果,并分析了(HP)感染与胃部疾病的相关性。纳入的儿童被随机分为 A 组(接受标准三联疗法治疗)和 B 组(在 A 组治疗方法的基础上预先给予益生菌),每组 48 例。观察儿童的胃肠血管造影结果。以尿素呼气试验(UBT)结果为金标准,评估基于智能算法的胃肠血管造影的准确性。结果如下:首先,治疗前后胃肠 X 射线成像显示 B 组儿童胃体和胃窦黏膜的恢复情况优于 A 组( < 0.05);其次,HP 阳性患者的胃肠道疾病发生率为 78%,HP 阴性患者的发生率为 32%;第三,基于智能算法的胃肠 X 射线成像的灵敏度、特异性和准确性分别为 76.47%、93.67%和 90.63%。治疗后,B 组肿瘤坏死因子(TNF-)和白细胞介素 6(IL-6)明显低于 A 组( < 0.05),B 组不良反应发生率明显低于 A 组( < 0.05)。综上所述,基于智能算法的胃肠 X 射线成像对胃肠道 HP 感染的判断具有可靠的参考价值,益生菌联合三联疗法对 HP 感染更有效,值得临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1577/8977303/c0b2faee3889/CMMI2022-8464361.001.jpg

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