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富血小板血浆(PRP)病灶内注射治疗网球肘的功能结局——一项前瞻性队列研究。

Functional Outcome of Platelet-Rich Plasma (PRP) Intra-lesional Injection for Tennis Elbow - A Prospective Cohort Study.

作者信息

Paramanantham Madhavan, Seenappa Hariprasad, Venkataraman Sagar, Shanthappa Arun H

机构信息

Orthopaedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy Of Higher Education and Research, Kolar, IND.

Orthopaedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, IND.

出版信息

Cureus. 2022 Mar 8;14(3):e22974. doi: 10.7759/cureus.22974. eCollection 2022 Mar.

DOI:10.7759/cureus.22974
PMID:35415041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8990042/
Abstract

Introduction Platelet-Rich Plasma (PRP) is an autologous human plasma preparation with a higher platelet concentration. Injection of PRP were, found to be effective in treating tendinopathy and arthritis. A few studies only focused in using PRP injection in patients with tennis elbow. This study was conducted to access the functional outcome of PRP injection in tennis elbow patients. Methodology A prospective study was done from June 2020 to June 2021, at R. L. Jalappa Hospital, Kolar, India among 80 individuals diagnosed with tennis elbow. All individuals aged between 18 to 65 years of either gender and the pain symptoms not subsided with oral analgesics or physiotherapy were included in this study. We analysed all the patients with a MAYO elbow performance score and Visual Analogue Pain Scale (VAS) during the follow-up period. Results In total, 80 individuals participated in our study, of which the mean age of the participants was 45.54. There is statistical significance in the difference of means of pain score obtained using both VAS and MAYO score at 12 weeks and 24 weeks. There is high significant positive correlation of age with the pain scores at 12th week and 24th week after the procedure. Conclusion In tennis elbow patients, PRP injection shows an effective reduction in pain according to VAS and MAYO score and especially, younger age patients have shown more benefit in terms of pain reduction with PRP treatment.

摘要

引言 富血小板血浆(PRP)是一种血小板浓度较高的自体人血浆制剂。已发现注射PRP对治疗肌腱病和关节炎有效。仅有少数研究专注于对网球肘患者使用PRP注射。本研究旨在评估PRP注射对网球肘患者的功能疗效。方法 于2020年6月至2021年6月在印度科拉尔的RL贾拉帕医院对80例被诊断为网球肘的个体进行了一项前瞻性研究。纳入本研究的所有个体年龄在18至65岁之间,性别不限,且疼痛症状未因口服镇痛药或物理治疗而缓解。在随访期间,我们使用梅奥肘关节功能评分和视觉模拟疼痛量表(VAS)对所有患者进行了分析。结果 共有80人参与了我们的研究,参与者的平均年龄为45.54岁。在12周和24周时,使用VAS和梅奥评分获得的疼痛评分均值差异具有统计学意义。术后第12周和第24周,年龄与疼痛评分之间存在高度显著的正相关。结论 在网球肘患者中,根据VAS和梅奥评分,PRP注射显示出有效的疼痛减轻,特别是年轻患者在接受PRP治疗后在疼痛减轻方面表现出更大的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503e/8990042/b7926689d33d/cureus-0014-00000022974-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503e/8990042/b7926689d33d/cureus-0014-00000022974-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503e/8990042/b7926689d33d/cureus-0014-00000022974-i01.jpg

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Shoulder Elbow. 2020 Feb;12(1):46-53. doi: 10.1177/1758573218809467. Epub 2018 Nov 12.
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Medicine (Baltimore). 2019 Dec;98(51):e18358. doi: 10.1097/MD.0000000000018358.
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