Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore-560012, India.
Chem Commun (Camb). 2022 May 5;58(37):5558-5573. doi: 10.1039/d2cc01014c.
Research on organic cages has blossomed over the past few years into a mature field of study which can contribute to solving some of the challenging problems. In this review we aim to showcase the recent trends in synthesis of organic cages including a brief discussion on their use in catalysis, gas sorption, host-guest chemistry and energy transfer. Among the organic cages, water-soluble analogues are a special class of compounds which have gained renewed attention in recent times. Due to their advantage of being compatible with water, such cages have the potential of showing biomimetic activities and can find use in drug delivery and also as hosts for catalysis in aqueous medium. Hence, the synthetic strategies for the formation of water-soluble organic cages shall be discussed along with their potential applications.
近年来，有机笼的研究蓬勃发展，成为一个成熟的研究领域，有望为解决一些具有挑战性的问题做出贡献。在这篇综述中，我们旨在展示有机笼合成的最新趋势，包括简要讨论它们在催化、气体吸附、主客体化学和能量转移方面的应用。在有机笼中，水溶性类似物是一类特殊的化合物，近年来重新引起了人们的关注。由于其与水相兼容的优势，这些笼状化合物具有表现出仿生活性的潜力，并可用于药物传递以及作为水相催化的主体。因此，将讨论水溶性有机笼形成的合成策略及其潜在应用。
