Rondouin G, Lerner-Natoli M, Hashizume A
Exp Neurol. 1987 Feb;95(2):500-5. doi: 10.1016/0014-4886(87)90156-7.
Wet dog shake behavior was studied in different models of epilepsy in the rat. Numerous wet dog shakes were associated with limbic seizures in the course of focal epilepsy induced by kindling stimulations or local injections of kainic or quisqualic acid and progressively disappeared during generalization. On the contrary, they were never observed in models of generalized epilepsy. This study suggests that the number of wet dog shakes may be an index of the progression of limbic seizures toward generalization.
在大鼠的不同癫痫模型中对湿狗摇行为进行了研究。在通过点燃刺激或局部注射 kainic 酸或喹啉酸诱导的局灶性癫痫过程中,大量湿狗摇与边缘性癫痫发作相关,并且在发作泛化期间逐渐消失。相反,在全身性癫痫模型中从未观察到这种行为。这项研究表明,湿狗摇的次数可能是边缘性癫痫发作向全身性发作进展的一个指标。