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各种毒液对大肠杆菌的作用。

The action of various venoms on Escherichia coli.

作者信息

Stocker J F, Traynor J R

出版信息

J Appl Bacteriol. 1986 Nov;61(5):383-8. doi: 10.1111/j.1365-2672.1986.tb04300.x.

DOI:10.1111/j.1365-2672.1986.tb04300.x
PMID:3542922
Abstract

The antibacterial activity of honeybee venom (Apis mellifera), three snake venoms (Naja naja sputatrix, Vipera russellii and Crotalus adamanteus) and the polypeptide melittin was investigated against Escherichia coli. Minimum inhibitory concentration values, cell lysis and alterations in cell permeability were determined and action against E. coli was in the order: A. mellifera venom greater than melittin greater than N. naja sputatrix venom much greater than V. russellii venom greater than C. adamanteus venom. Cellular damage by A. mellifera and N. naja sputatrix venoms was evident in electron micrographs.

摘要

研究了蜜蜂毒液(意大利蜜蜂)、三种蛇毒(眼镜蛇、罗素蝰蛇和矛头蝮蛇)以及多肽蜂毒肽对大肠杆菌的抗菌活性。测定了最低抑菌浓度值、细胞裂解和细胞通透性的变化,它们对大肠杆菌的作用顺序为:意大利蜜蜂毒液>蜂毒肽>眼镜蛇毒液>>罗素蝰蛇毒液>矛头蝮蛇毒液。在电子显微镜照片中,意大利蜜蜂毒液和眼镜蛇毒液对细胞的损伤很明显。

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