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可见光与皮肤

Visible Light and the Skin.

作者信息

Ezekwe Nneamaka, Maghfour Jalal, Kohli Indermeet

机构信息

Department of Dermatology, University of Colorado, Aurora, CO, USA.

Photomedicine and Photobiology Unit, Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.

出版信息

Photochem Photobiol. 2022 Nov;98(6):1264-1269. doi: 10.1111/php.13634. Epub 2022 May 10.

Abstract

Visible light (VL, 400-700 nm) was previously regarded as nonsignificant with minimal to no photobiologic effects on the skin. Recent studies have demonstrated that in dark-skinned individuals (skin phototypes IV-VI), VL can induce more intense and longer lasting pigmentation compared to ultraviolet A1 (UVA1, 340-400 nm). Additionally, long wavelength UVA1 (370-400 nm) has been shown to potentiate these effects of VL. The combination of VL and UVA1 (VL + UVA1, 370-700 nm) was also able to induce erythema in light-skinned individuals (skin phototypes I-III), which is a novel finding since the erythemogenic spectrum of sunlight has primarily been attributed to ultraviolet B (UVB, 290-320 nm) and short wavelength UVA2 (320-340 nm) only. Although biologic effects of VL + UVA1 have been established, there are no guidelines in any country to test for photoprotection against this waveband. This invited perspective aims to present the evolution of knowledge of photobiologic effects of VL, associated phototesting methodologies, and current position on VL photoprotection.

摘要

可见光(VL,400 - 700纳米)曾被认为无足轻重,对皮肤的光生物学效应微乎其微或几乎没有。最近的研究表明,在深色皮肤个体(皮肤光类型IV - VI)中,与紫外线A1(UVA1,340 - 400纳米)相比,VL可诱导更强烈、更持久的色素沉着。此外,长波长UVA1(370 - 400纳米)已被证明可增强VL的这些效应。VL和UVA1的组合(VL + UVA1,370 - 700纳米)也能够在浅色皮肤个体(皮肤光类型I - III)中诱导红斑,这是一个新发现,因为阳光的致红斑光谱以前主要仅归因于紫外线B(UVB,290 - 320纳米)和短波长UVA2(320 - 340纳米)。尽管VL + UVA1的生物学效应已得到证实,但任何国家都没有针对该波段光防护测试的指南。这篇特邀观点旨在介绍VL光生物学效应的知识演变、相关的光测试方法以及VL光防护的当前状况。

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