Department of Pulmonary and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Department of Respiratory and Critical Care Medicine, Foshan Second People's Hospital, Affiliated Foshan Hospital of Southern Medical University, Foshan, Guangdong, China.
Arch Bronconeumol. 2022 Apr;58:32-38. doi: 10.1016/j.arbres.2022.03.006. Epub 2022 Apr 13.
As with the rapid increase of the number of patients who have recovered from COVID-19 globally, there needs to be a major shift of the focus from rapid pathogen detection, treatment and prevention to the promotion of better recovery. Notwithstanding the scarcity of our understandings, recent studies have unraveled a plethora of pulmonary and systemic consequences which require medical attention. These consequences remained as of the end of follow-up which ranged from 1 month to 1 year. Here, we review the consequences of COVID-19 in terms of the residual symptoms, radiological and functional manifestations, and identify the potential risk factors that contribute to a prolonged recovery. We also summarize the benefits of clinical interventions (particularly the pulmonary rehabilitation program), and address several undetermined concerns and key future research directions.
随着全球范围内 COVID-19 康复患者数量的快速增加，我们需要将重点从快速病原体检测、治疗和预防转移到促进更好的康复上来。尽管我们对其了解甚少，但最近的研究已经揭示了许多需要医疗关注的肺部和全身后果。这些后果在随访结束时仍然存在，时间从 1 个月到 1 年不等。在这里，我们从残留症状、影像学和功能表现等方面综述了 COVID-19 的后果，并确定了导致康复时间延长的潜在危险因素。我们还总结了临床干预的益处（特别是肺康复计划），并解决了几个尚未确定的问题和关键的未来研究方向。
