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儿童复杂性阑尾炎精准诊断的相关标志物

Related Markers for the Precision Diagnosis of Complex Appendicitis in Children.

作者信息

Zhou Jialin, Xu Wenjing, Wang Jitao, Fan Zhe

机构信息

Department of General Surgery, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.

Department of Central Laboratory, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.

出版信息

Front Pharmacol. 2022 Mar 31;13:865303. doi: 10.3389/fphar.2022.865303. eCollection 2022.

DOI:10.3389/fphar.2022.865303
PMID:35431963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9010144/
Abstract

Acute appendicitis is the most common surgical emergency in children. Despite the high incidence rate of appendicitis, it is sometimes misdiagnosed or missed. Complex appendicitis (CA) in children is characterized by a critical condition, several complications, and high mortality. Precision distinguishing between simple appendicitis and CA correctly is key to choosing appropriate treatment. A safe, cheap, rapid, extensive and accurate diagnostic marker of appendicitis will be of great significance for emergency general surgeons to treat suspected CA. Many studies have investigated possible diagnostic markers for the diagnosis of CA in children. In this study, studies related to CA in children in recent years are summarized, and the related markers and scoring system for the diagnosis of CA in children are summarized.

摘要

急性阑尾炎是儿童最常见的外科急症。尽管阑尾炎发病率很高,但有时仍会被误诊或漏诊。儿童复杂性阑尾炎(CA)的特点是病情危急、并发症多且死亡率高。准确区分单纯性阑尾炎和CA是选择合适治疗方法的关键。一种安全、廉价、快速、广泛且准确的阑尾炎诊断标志物对于急诊普通外科医生治疗疑似CA具有重要意义。许多研究探讨了儿童CA诊断的可能标志物。本研究总结了近年来儿童CA的相关研究,并总结了儿童CA诊断的相关标志物和评分系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5090/9010144/49f099bc9636/fphar-13-865303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5090/9010144/49f099bc9636/fphar-13-865303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5090/9010144/49f099bc9636/fphar-13-865303-g001.jpg

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Surg Infect (Larchmt). 2021 Dec;22(10):1064-1071. doi: 10.1089/sur.2021.107. Epub 2021 Aug 9.
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Predictive factors of perforated appendicitis: Impact of the C-reactive protein level.穿孔性阑尾炎的预测因素:C反应蛋白水平的影响。
Surg Open Sci. 2021 Jun 30;6:1-4. doi: 10.1016/j.sopen.2021.06.003. eCollection 2021 Oct.
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Serum Soluble CD40 Ligand in Predicting Simple Appendicitis and Complicated Appendicitis at Different Time Points in Children.
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Front Pediatr. 2021 Jun 9;9:676370. doi: 10.3389/fped.2021.676370. eCollection 2021.
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