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2 型糖尿病患者血糖控制相关因素的横断面研究。

Factors associated with glycemic control among patients with type 2 diabetes: a cross-sectional study.

机构信息

Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.

出版信息

Eur Rev Med Pharmacol Sci. 2022 Apr;26(7):2415-2421. doi: 10.26355/eurrev_202204_28475.

Abstract

OBJECTIVE

Achieving glycemic control significantly improves the progression of the disease among diabetes mellitus patients although this is not achieved by many diabetics. The aim of the study is to explore the factors associated with glycemic control among patients with type 2 diabetes.

PATIENTS AND METHODS

In addition to sociodemographic variables, beliefs about medications and medication adherence were evaluated using the validated Beliefs about Medications Questionnaire and the 4-item medication adherence scale. A cut-off point of HbA1c% <7 was used as an indicator of glycemic control. Stepwise binary logistic regression was conducted to explore the variables associated with poor glycemic control.

RESULTS

A total of 287 patients participated in the study. More than half (58%) were found to have poor glycemic control‎. Females had significantly higher odds of having controlled diabetes (OR=2.28, p-value <0.01). Increasing necessity for diabetes medications was significantly associated with improved glycemic control (OR=2.75, p-value <0.01). Participants in low or moderate adherence groups had significantly higher odds of having uncontrolled diabetes.

CONCLUSIONS

Future diabetes management programs should focus on emphasizing medication necessity and improving medication adherence, particularly for male patients, with the aim of improving glycemic control and health outcomes among patients with type 2 diabetes.

摘要

目的

尽管许多糖尿病患者无法实现血糖控制,但控制血糖水平显著改善了糖尿病患者的病情进展。本研究旨在探讨 2 型糖尿病患者血糖控制的相关因素。

患者和方法

除了社会人口统计学变量外,还使用经过验证的药物信念问卷和 4 项药物依从性量表评估了患者对药物的信念和药物依从性。以糖化血红蛋白(HbA1c)%<7 作为血糖控制的指标。采用逐步二分类逻辑回归分析探讨与血糖控制不佳相关的变量。

结果

共有 287 名患者参与了这项研究。超过一半(58%)的患者血糖控制不佳。女性控制糖尿病的几率明显更高(OR=2.28,p 值<0.01)。对糖尿病药物的必要性增加与血糖控制的改善显著相关(OR=2.75,p 值<0.01)。低或中依从性组的参与者控制不佳的糖尿病的几率明显更高。

结论

未来的糖尿病管理项目应重点强调药物的必要性和提高药物依从性,特别是针对男性患者,以改善 2 型糖尿病患者的血糖控制和健康结果。

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