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接受透析的终末期肾病患者的易感因素与尿毒症心包积液

Predisposing factors and uremic pericardial effusion among ESRD patients undergoing dialysis.

作者信息

Aghsaeifard Ziba, Firouzi Rahim, Alizadeh Reza

机构信息

Department of Internal Medicine, School of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Cardiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Ann Med Surg (Lond). 2022 Apr 6;77:103579. doi: 10.1016/j.amsu.2022.103579. eCollection 2022 May.

Abstract

OBJECTIVE

Pericardial effusion and pericarditis are responsible for 3-5% of deaths due to tamponade, fatal arrhythmia and heart failure. Improvement in dialysis methods has allowed the initiation of the treatment at early stages. This study is designed to evaluate the prevalence of pericardial effusion and its predisposing factors among end-stage renal disease (ESRD) patients undergoing dialysis.

METHODS

This is a cross-sectional study that included patients from the two Medical Centers in (XXX). These patients were presented with ESRD with a GFR <10 cc/min and were under long-term dialysis, also called chronic hemodialysis. The echocardiography was performed and patients with pericarditis and/or pericardial effusion due to non-uremic causes or dialysis were excluded.

RESULTS

Of 132 patients included, mild pericardial effusion was observed in 17(12.9%) patients, 8(6.1%) patients were presented with moderate and 1 (0.7%) had severe pericardial effusion. Among females, 9(15.8%) showed pericardial effusion whereas, it was reported in 8(10.7%) males, with no statistically significant difference. Furthermore, no significant difference was seen in the ages or etiologies of patients with or without pericardial effusion (50.5 ± 15.5 vs 52.8 ± 16.1, respectively).

CONCLUSION

Our study reports that echocardiography among dialysis patients is likely to determine the effectiveness of the dialysis procedure and can be a cost-effective approach. Futher studies regarding laboratory parameters are required in this area.

摘要

目的

心包积液和心包炎导致的心包填塞、致命性心律失常及心力衰竭占死亡原因的3% - 5%。透析方法的改进使治疗能够在早期启动。本研究旨在评估接受透析的终末期肾病(ESRD)患者中心包积液的患病率及其易感因素。

方法

这是一项横断面研究,纳入了来自(XXX)两个医疗中心的患者。这些患者为GFR <10 cc/min的ESRD患者,正在接受长期透析,即慢性血液透析。进行了超声心动图检查,并排除了因非尿毒症原因或透析导致的心包炎和/或心包积液患者。

结果

在纳入的132例患者中,17例(12.9%)观察到轻度心包积液,8例(6.1%)为中度,1例(0.7%)为重度心包积液。女性中有9例(15.8%)出现心包积液,男性中有8例(10.7%)出现,差异无统计学意义。此外,有无心包积液患者的年龄或病因无显著差异(分别为50.5 ± 15.5和52.8 ± 16.1)。

结论

我们的研究报告称,透析患者的超声心动图检查可能有助于确定透析程序的有效性,且可能是一种具有成本效益的方法。该领域还需要进一步开展关于实验室参数的研究。

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