Sawicka-Gutaj Nadia, Erampamoorthy Abikasinee, Zybek-Kocik Ariadna, Kyriacou Angelos, Zgorzalewicz-Stachowiak Małgorzata, Czarnywojtek Agata, Ruchała Marek
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
CEDM, Centre of Endocrinology, Diabetes and Metabolism, Limassol 3075, Cyprus.
Metabolites. 2022 Apr 7;12(4):336. doi: 10.3390/metabo12040336.
Nowadays obesity becomes a significant global problem. Hence, recently more and more attention has been paid to substances present in the body that have a significant impact on metabolic processes and thermogenesis, in the context of their potential use in the prevention and treatment of obesity. It is well known that the relationship between thyroid hormones and obesity is multilayered, however recently, more and more information about the possible relation between thyroid hormones and muscle metabolism has been published. The aim of this review is to present the most updated information on the physiological impact of thyroid hormones on muscle tissue, as well as pathological changes related to the occurrence of various types of thyroid disorders, including hypothyroidism, hyperthyroidism and sick euthyroid syndrome. However, the data in humans still remains insufficient, and further studies are needed to fully explore the thyroid-muscle cross-talk.
如今，肥胖已成为一个重大的全球性问题。因此，近来人们越来越关注体内存在的、对代谢过程和产热有重大影响的物质，考虑到它们在肥胖预防和治疗中的潜在用途。众所周知，甲状腺激素与肥胖之间的关系是多层面的，然而最近，越来越多关于甲状腺激素与肌肉代谢之间可能关系的信息已被发表。本综述的目的是呈现关于甲状腺激素对肌肉组织生理影响的最新信息，以及与各种甲状腺疾病（包括甲状腺功能减退、甲状腺功能亢进和亚临床甲状腺功能异常综合征）发生相关的病理变化。然而，人类方面的数据仍然不足，需要进一步研究以充分探索甲状腺与肌肉之间的相互作用。
