Effects of baffle and intraocular pressure on aerosols generated in the noncontact tonometer measurement during COVID-19.

AIM

To investigate the effects of baffle and intraocular pressure (IOP) on the aerosols generated in the noncontact tonometer (NCT) measurement and provide recommendations for the standardized use of the NCT during coronavirus disease 2019 (COVID-19).

METHODS

This clinical trial included 252 subjects (312 eyes) in The Eye Hospital, Wenzhou Medical University from March 7, 2020, to March 28, 2020. Sixty subjects (120 eyes) with normal IOP were divided into two groups. One group used an NCT without a baffle, another group used an NCT with a baffle. Another 192 subjects (192 eyes) were divided into four groups: Group A (without a baffle+normal IOP), Group A (without a baffle+high IOP), Group B (with a baffle+normal IOP) and Group B (with a baffle+high IOP). Particulate matter (PM) 2.5 and PM10 generated by all subjects were quantified during the NCT measurement. The IOP values were recorded simultaneously. Effects of baffle and IOP on aerosols generated during the NCT measurement were analyzed.

RESULTS

In the normal eye group with a baffle, the aerosol density decreased in a wave-like shape near the NCT with the increase in the number of people measured for IOP, demonstrating no cumulative effect. However, in the normal eye group without a baffle, there was a cumulative effect. PM2.5 and PM10 in Group A were higher than Group A (both <0.001). The PM2.5 and PM10 in Group B were higher than Group B (<0.01, <0.001 respectively). The PM10 of Group B was lower than Group A (<0.01). PM2.5 in Group B were lower than Group A (<0.01). The median of per capita PM2.5 and PM10 in the combined Group A+A were 0.80 and 1.10 µg/m respectively, which were higher than 0.20 and 0.60 µg/m in the combined Group B+B (both <0.01). The median of per capita PM2.5 and PM10 in the combined Group A+B were 0.10 and 0.20 µg/m respectively, which were lower than 1.30 and 1.70 µg/m in the combined Group A+B (both <0.001).

CONCLUSION

More aerosols could be generated in patients with high IOP. After the NCT is equipped with a baffle, per capita aerosol density generated decreased significantly near the NCT; And with the increase in the number of people measured for IOP, the aerosols gradually dissipated near the NCT, demonstrating no cumulative effect. Therefore, it is suggested that the NCT should be equipped with a baffle, especially for patients with high IOP.