French national institute for statistical and economic studies (INSEE), Montrouge, France.
The Health and Solidarity Ministerial Statistical Department (DREES), Paris, France.
Euro Surveill. 2022 Apr;27(16). doi: 10.2807/1560-7917.ES.2022.27.16.2200250.
We assessed the protection conferred by naturally-acquired, vaccine-induced and hybrid immunity during the concomitant Omicron and Delta epidemic waves in France on symptomatic infection and severe COVID-19. The greatest levels of protection against both variants were provided by hybrid immunity. Protection against Omicron symptomatic infections was systematically lower and waned at higher speed than against Delta in those vaccinated. In contrast, there were little differences in variant-specific protection against severe inpatient outcomes in symptomatic individuals.
我们评估了在法国奥密克戎和德尔塔流行期间，自然感染、疫苗诱导和混合免疫带来的对有症状感染和重症 COVID-19 的保护作用。针对这两种变异株，混合免疫提供了最大程度的保护。与德尔塔相比，在已接种疫苗的人群中，针对奥密克戎有症状感染的保护作用系统性较低且衰减速度更快。相比之下，针对有症状个体的重症住院结局，针对两种变异株的特异性保护作用差异不大。
Zotero 插件