瞬时受体电位（TRP）通道：癌症的标志物和治疗靶点？
Transient Receptor Potential (TRP) Channels: Markers and Therapeutic Targets for Cancer?
机构信息
School of Pharmacy, Section of Experimental Medicine, University of Camerino, 62032 Camerino, Italy.
School of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.
出版信息
Biomolecules. 2022 Apr 6;12(4):547. doi: 10.3390/biom12040547.
Abstract
This Special Issue in explores the roles of Transient Receptor Potential channels (TRPs) in cancer [...].
摘要
本特刊探讨了瞬时受体电位通道（TRP）在癌症中的作用[...]。
相似文献
1
Transient Receptor Potential (TRP) Channels: Markers and Therapeutic Targets for Cancer?瞬时受体电位（TRP）通道：癌症的标志物和治疗靶点？
Biomolecules. 2022 Apr 6;12(4):547. doi: 10.3390/biom12040547.
2
Oncogenic and anti-oncogenic effects of transient receptor potential channels.瞬时受体电位通道的致癌和抑癌作用。
Curr Top Med Chem. 2013;13(3):344-66. doi: 10.2174/1568026611313030011.
3
Transient receptor potential (TRP) channels in human colorectal cancer: evidence and perspectives.人类结直肠癌中的瞬时受体电位（TRP）通道：证据与展望。
Histol Histopathol. 2021 May;36(5):515-526. doi: 10.14670/HH-18-308. Epub 2021 Feb 2.
4
Temperature-sensitive transient receptor potential channels in corneal tissue layers and cells.角膜组织层和细胞中的温度敏感型瞬时受体电位通道
Ophthalmic Res. 2014;52(3):151-9. doi: 10.1159/000365334. Epub 2014 Oct 8.
5
TRP channels and cancer: new targets for diagnosis and chemotherapy.瞬时受体电位通道与癌症：诊断和化疗的新靶点
Endocr Metab Immune Disord Drug Targets. 2011 Mar;11(1):54-67. doi: 10.2174/187153011794982068.
6
An overview on transient receptor potential channels superfamily.瞬时受体电位通道超家族概述。
Behav Pharmacol. 2020 Aug;31(5):413-434. doi: 10.1097/FBP.0000000000000524.
7
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents.天然产物瞬时受体电位 (TRP) 通道调节剂作为潜在的抗癌药物。
Chem Soc Rev. 2016 Nov 7;45(22):6130-6137. doi: 10.1039/c5cs00916b.
8
Transient receptor potential channels and energy homeostasis.瞬时受体电位通道与能量平衡。
Trends Endocrinol Metab. 2013 Nov;24(11):554-60. doi: 10.1016/j.tem.2013.06.005. Epub 2013 Jul 24.
9
The Pivotal Role of TRP Channels in Homeostasis and Diseases throughout the Gastrointestinal Tract.TRP 通道在整个胃肠道稳态和疾病中的关键作用。
Int J Mol Sci. 2019 Oct 24;20(21):5277. doi: 10.3390/ijms20215277.
10
TRP channels in disease.疾病中的瞬时受体电位通道
Biochim Biophys Acta. 2007 Aug;1772(8):805-12. doi: 10.1016/j.bbadis.2007.02.002. Epub 2007 Feb 12.
引用本文的文献
1
TRP channels and cancer modulation: a voyage beyond metabolic reprogramming, oxidative stress and the advent of nanotechnologies in targeted therapy.瞬时受体电位通道与癌症调控：超越代谢重编程、氧化应激以及靶向治疗中纳米技术出现的探索之旅。
J Exp Clin Cancer Res. 2025 Aug 14;44(1):240. doi: 10.1186/s13046-025-03495-4.
2
TRP channels and breast cancer: the role of TRPs in the pathophysiological development.瞬时受体电位通道与乳腺癌：瞬时受体电位通道在病理生理发展中的作用
Front Mol Biosci. 2025 Feb 26;12:1528663. doi: 10.3389/fmolb.2025.1528663. eCollection 2025.
3
TRPC6 is a Biomarker for Prognosis and Immunotherapy of Stomach Adenocarcinoma Based on Bioinformatic Analysis and Experimental Validation.基于生物信息学分析和实验验证，瞬时受体电位阳离子通道蛋白6（TRPC6）是胃腺癌预后和免疫治疗的生物标志物。
Immunotargets Ther. 2024 Dec 12;13:735-748. doi: 10.2147/ITT.S488953. eCollection 2024.
4
Analysis of mRNA expression profile in the treatment of diabetic foot ulcer healing by tibial cortex transverse distraction.胫骨皮质横向牵张治疗糖尿病足溃疡愈合过程中 mRNA 表达谱分析。
Sci Rep. 2024 Oct 22;14(1):24865. doi: 10.1038/s41598-024-76291-3.
5
TRPV3 regulates Breast Cancer Cell Proliferation and Apoptosis by EGFR/AKT pathway.瞬时受体电位香草酸亚型3（TRPV3）通过表皮生长因子受体（EGFR）/蛋白激酶B（AKT）信号通路调控乳腺癌细胞的增殖和凋亡。
J Cancer. 2024 Mar 25;15(10):2891-2899. doi: 10.7150/jca.93940. eCollection 2024.
6
Transient receptor potential channels as predictive marker and potential indicator of chemoresistance in colon cancer.瞬时受体电位通道作为结肠癌化疗耐药的预测标志物和潜在指标。
Oncol Res. 2023 Nov 15;32(1):227-239. doi: 10.32604/or.2023.043053. eCollection 2023.
7
Cannabigerolic Acid (CBGA) Inhibits the TRPM7 Ion Channel Through its Kinase Domain.大麻素二酸（CBGA）通过其激酶结构域抑制 TRPM7 离子通道。
Function (Oxf). 2023 Dec 7;5(1):zqad069. doi: 10.1093/function/zqad069. eCollection 2024.
8
The Emergence of TRP Channels Interactome as a Potential Therapeutic Target in Pancreatic Ductal Adenocarcinoma.瞬时受体电位通道相互作用组作为胰腺导管腺癌潜在治疗靶点的出现
Biomedicines. 2023 Apr 13;11(4):1164. doi: 10.3390/biomedicines11041164.
9
Transient Receptor Potential (TRP) Channels in Pain, Neuropsychiatric Disorders, and Epilepsy.瞬时受体电位 (TRP) 通道在疼痛、神经精神疾病和癫痫中的作用。
Int J Mol Sci. 2023 Mar 1;24(5):4714. doi: 10.3390/ijms24054714.
10
Deregulated calcium signaling in blood cancer: Underlying mechanisms and therapeutic potential.血液癌症中失调的钙信号传导：潜在机制与治疗潜力
Front Oncol. 2022 Oct 18;12:1010506. doi: 10.3389/fonc.2022.1010506. eCollection 2022.
本文引用的文献
1
The Mucolipin TRPML2 Channel Enhances the Sensitivity of Multiple Myeloma Cell Lines to Ibrutinib and/or Bortezomib Treatment.Mucolipin TRPML2 通道增强多发性骨髓瘤细胞系对伊布替尼和/或硼替佐米治疗的敏感性。
Biomolecules. 2022 Jan 9;12(1):107. doi: 10.3390/biom12010107.
2
TRP Channels as Molecular Targets to Relieve Cancer Pain.TRP 通道作为缓解癌症疼痛的分子靶点。
Biomolecules. 2021 Dec 21;12(1):1. doi: 10.3390/biom12010001.
3
Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.溶酶体阳离子通道和 MITF 在黑素细胞和黑色素瘤中的作用
Biomolecules. 2021 Jul 13;11(7):1021. doi: 10.3390/biom11071021.
4
TRPV Protein Family-From Mechanosensing to Cancer Invasion.TRPV 蛋白家族——从机械感知到癌症侵袭。
Biomolecules. 2021 Jul 13;11(7):1019. doi: 10.3390/biom11071019.
5
Transient Receptor Potential (TRP) Channels in Haematological Malignancies: An Update.血液系统恶性肿瘤中的瞬时受体电位 (TRP) 通道：最新进展。
Biomolecules. 2021 May 20;11(5):765. doi: 10.3390/biom11050765.
6
TRPM4 in Cancer-A New Potential Drug Target.TRPM4 在癌症中的作用——一个新的潜在药物靶点。
Biomolecules. 2021 Feb 5;11(2):229. doi: 10.3390/biom11020229.
Zotero 插件