Department of Microbiology and Virology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiellońska 4, 41-200 Sosnowiec, Poland.
Int J Mol Sci. 2022 Apr 13;23(8):4298. doi: 10.3390/ijms23084298.
is a bacterium that is part of the human microbiota. It is most abundant on the skin, in the respiratory system and in the human digestive tract. Also, contributes to human infections and has a high mortality rate. Both of these bacterial species produce biofilm, a pathogenic factor increasing their resistance to antibiotics. For this reason, we are looking for new substances that can neutralize bacterial cells. One of the best-known substances with such effects are silver nanoparticles. They exhibited antibacterial and antibiofilm formation activity that depended on their size, shape and the concentration used. In this review, we presented the data related to the use of silver nanoparticles in counteracting bacterial growth and biofilm formation published in scientific papers between 2017 and 2021. Based on the review of experimental results, the properties of nanoparticles prompt the expansion of research on their activity.
是一种存在于人体微生物群中的细菌。它在皮肤、呼吸系统和人类消化道中最为丰富。此外，它会导致人体感染，并具有很高的死亡率。这两种细菌都能产生生物膜，这一致病因素增加了它们对抗生素的耐药性。出于这个原因，我们正在寻找可以中和细菌细胞的新物质。具有这种作用的最著名的物质之一是银纳米粒子。它们表现出的抗菌和抗生物膜形成活性取决于它们的大小、形状和使用浓度。在这篇综述中，我们介绍了 2017 年至 2021 年期间在科学论文中发表的关于银纳米粒子在对抗细菌生长和生物膜形成方面的应用数据。基于对实验结果的回顾，纳米粒子的特性促使人们对其活性展开了进一步的研究。
