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每日环境空气污染与哮喘患者的肺功能、哮喘症状发生和急救吸入器使用之间的关联。

Associations between Daily Ambient Air Pollution and Pulmonary Function, Asthma Symptom Occurrence, and Quick-Relief Inhaler Use among Asthma Patients.

机构信息

Department of Environmental Health, Faculty of Health Sciences, Jagiellonian University Medical College, 31066 Krakow, Poland.

出版信息

Int J Environ Res Public Health. 2022 Apr 16;19(8):4852. doi: 10.3390/ijerph19084852.

Abstract

Particulate matter (PM) is harmful to human health, especially for people with asthma. The goal of this study was to enhance the knowledge about the short-term effects of daily air concentrations of PM on health outcomes among asthma patients. The novelty of this study was the inclusion of a homogeneous group of patients (N = 300) with diagnosed and partly controlled asthma. Patients recorded their symptoms, asthma quick-relief inhaler use, and peak expiratory flow (PEF) measurements in a diary for two weeks. Data on particulate air pollution were obtained from stationary monitoring stations. We have shown that particulate pollutants (PM and PM) are associated with significant deterioration of PEF and an increase in the frequency of early asthma symptoms, as well as asthma quick-relief inhaler use. These effects are observed not only on the day of exposure, but also on the following day. For public health practice, these results support the rationale for using peak-flow meters as necessary devices for proper asthma self-management and control, especially in locations where the air is polluted with particles. This may decrease the number of asthma patients seeking medical help.

摘要

颗粒物(PM)对人类健康有害,尤其是对哮喘患者。本研究的目的是提高对每日空气中 PM 浓度对哮喘患者健康结果的短期影响的认识。本研究的新颖之处在于纳入了一组同质的患者(N=300),他们患有确诊且部分得到控制的哮喘。患者在两周内通过日记记录他们的症状、哮喘急救吸入器的使用情况和呼气峰流速(PEF)测量值。颗粒物空气污染数据来自固定监测站获得。我们已经表明,颗粒物污染物(PM 和 PM)与 PEF 显著恶化以及哮喘早期症状发生频率增加以及哮喘急救吸入器使用增加有关。这些影响不仅在暴露当天观察到,而且在第二天也观察到。对于公共卫生实践,这些结果支持使用峰流速计作为适当的哮喘自我管理和控制的必要设备的理由,特别是在空气受到颗粒物污染的地方。这可能会减少寻求医疗帮助的哮喘患者数量。

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The association of exposure to PM with the quality of life in adult asthma patients.大气细颗粒物暴露与成人哮喘患者生活质量的关系。
Int J Occup Med Environ Health. 2020 Apr 30;33(3):311-324. doi: 10.13075/ijomeh.1896.01527. Epub 2020 Mar 26.

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