Department of Environmental Health, Faculty of Health Sciences, Jagiellonian University Medical College 20 Grzegorzecka St., PL 31531 Krakow, Poland.
Int J Environ Res Public Health. 2019 Jul 13;16(14):2502. doi: 10.3390/ijerph16142502.
While the negative influence of environmental pollution on the respiratory system is well established, especially for people with bronchial hyper-reactivity, the impact of particulate matter on quality of life in asthma patients is not well understood. Three hundred adult asthma patients were recruited for a study; for each patient, the daily concentrations of particulate matter of 2.5 µm or less in diameter (PM) were recorded from air quality monitoring stations. The study was conducted over two weeks. After two weeks, the patients filled out the Asthma Quality of Life Questionnaire (AQLQ), evaluating the quality of their lives throughout the monitored period. Patients exposed to a higher concentration of PM had significantly lower AQLQ scores. Every 10 µg/m of an increase in the concentration of PM resulted in a decrease of the AQLQ score by 0.16. All domains of quality of life (symptoms, activity limitations, emotional functioning, and environmental stimuli) assessed in the questionnaire were negatively affected by PM. These findings provide an important argument in favor of educating physicians and patients and raising awareness about the detrimental health effects of air pollution. Improving the quality of life of people with asthma requires an immediate and substantial reduction of air pollution.
虽然环境污染对呼吸系统的负面影响已得到充分证实,尤其是对支气管高反应性的人群,但颗粒物对哮喘患者生活质量的影响尚未得到充分理解。本研究招募了 300 名成年哮喘患者;为每位患者记录了空气质量监测站中直径为 2.5 µm 或以下的颗粒物(PM)的日浓度。研究持续了两周。两周后,患者填写了哮喘生活质量问卷(AQLQ),评估了整个监测期间的生活质量。暴露于更高浓度 PM 的患者的 AQLQ 评分明显较低。PM 浓度每增加 10 µg/m,AQLQ 评分就会降低 0.16。问卷中评估的所有生活质量领域(症状、活动受限、情绪功能和环境刺激)都受到 PM 的负面影响。这些发现为教育医生和患者以及提高对空气污染对健康的有害影响的认识提供了一个重要的论据。要提高哮喘患者的生活质量,需要立即大幅减少空气污染。