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[精神分裂症中的淋巴细胞异常是免疫缺陷的反映吗?文献综述]

[Are lymphocytic anomalies in the schizophrenic a reflection of an immune deficit? Bibliographic review].

作者信息

Aboudar M, Lemoine P

出版信息

Encephale. 1986 Sep-Oct;12(5):269-71.

PMID:3545782
Abstract

Concerning schizophrenia, several immune abnormalities are noticed. Lymphocytes are the main known immune agents. The review of the literature suggests a reduction of T-lymphocytes and a possible increase of B-lymphocytes. These results suggest an alteration of the cells immunity processes but it is difficult to know if the reason is due to the disease or to the neuroleptic treatments. One hypothesis would assume the existence of anti-T-lymphocyte antibodies in the schizophrenic. This could also lead to a viral hypothesis.

摘要

关于精神分裂症,人们注意到了一些免疫异常情况。淋巴细胞是已知的主要免疫因子。文献综述表明T淋巴细胞减少,B淋巴细胞可能增加。这些结果提示细胞免疫过程发生了改变,但很难确定原因是疾病本身还是抗精神病药物治疗所致。一种假设认为精神分裂症患者体内存在抗T淋巴细胞抗体。这也可能引发病毒假说。

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