Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte, Natal, Brazil.
Department of Surgery, Federal University of Rio Grande do Norte, Natal, Brazil.
BMJ Open. 2022 Apr 22;12(4):e053436. doi: 10.1136/bmjopen-2021-053436.
Endoscopic sinus surgery (ESS) is a current procedure for treating patients with chronic rhinosinusitis (CRS). Image-guided surgery (IGS) for ESS may help reduce complications and improve precision. However, it is uncertain in which cases IGS is beneficial. This work aims to compare ESS with and without IGS in patients with CRS.
PubMed, Embase, Scopus, Web of Science, Scielo, Cochrane Central Register of Controlled Trials, CINAHL, LILACS and Clinicaltrials.gov will be searched for reported clinical trials comparing the quality of life and perioperative outcomes of ESS with and without navigation. The search is planned for 20 April 2022. Three independent authors will select eligible articles and extract their data. The risk of bias will be assessed using the Cochrane Handbook for Systematic Reviews of Interventions. The Grading of Recommendation Assessment, Development and Evaluation method will evaluate the strength of the evidence. Data synthesis will be performed using the Review Manager software V.5.4.1. To assess heterogeneity, I statistics will be computed. Additionally, meta-analysis will be performed if the included studies are sufficiently homogenous.
This study reviews published data, and thus it is not necessary to obtain ethical approval. The findings of this systematic review will be published in a peer-reviewed journal.
CRD42020214791.
内镜鼻窦手术（ESS）是目前治疗慢性鼻-鼻窦炎（CRS）患者的一种方法。ESS 的图像引导手术（IGS）可能有助于减少并发症并提高精度。然而，在哪些情况下 IGS 是有益的还不确定。这项工作旨在比较有和没有 IGS 的 ESS 在 CRS 患者中的效果。
将在 2022 年 4 月 20 日对 PubMed、Embase、Scopus、Web of Science、Scielo、Cochrane 中央对照试验注册库、CINAHL、LILACS 和 Clinicaltrials.gov 进行检索，以比较有和没有导航的 ESS 的生活质量和围手术期结局的报告临床试验。将由三名独立作者选择合格的文章并提取其数据。使用 Cochrane 干预措施系统评价手册评估偏倚风险。使用推荐评估、制定和评估分级法（Grading of Recommendation Assessment, Development and Evaluation，GRADE）评估证据的强度。使用 Review Manager 软件 V.5.4.1 进行数据综合。为了评估异质性，将计算 I 统计量。如果纳入的研究足够同质，则进行荟萃分析。
这项研究回顾了已发表的数据，因此不需要获得伦理批准。本系统评价的结果将发表在同行评议的期刊上。
PROSPERO 注册号：CRD42020214791。
