Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, China.
Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
BMJ Open. 2022 Apr 22;12(4):e059176. doi: 10.1136/bmjopen-2021-059176.
(CT) causes the most prevalent bacterial sexually transmitted infection in the world, and men who have sex with men (MSM) are considered as a high-risk population for this infection. Data regarding the prevalence of CT infection in China are limited and fragmented. In this study, we aim to determine at the national level the anatomically specific CT prevalence and genotype distribution of CT strains among MSM, recruiting from the venues where MSM commonly seek sexual partners.
The study will be a nationwide cross-sectional survey to estimate the prevalence of chlamydial infections among MSM who meet the inclusion criteria over a period of 6 months (May-October 2022). A total of 2429 participants will be recruited from the venues where MSM most often seek sex partners in 14 cities of the 7 geographical regions in China. A mobile phone app-based anonymous self-administered questionnaire will be used to collect sociodemographic and behavioural data, and specimens of urine, anorectal and pharyngeal swabs will be collected for identifying the infections of CT and and genotypes of CT. The data will be analysed using the IBM SPSS program V.20 ETHICS AND DISSEMINATION: The study protocol has been approved by the Medical Ethics Committee of the Chinese Academy of Medical Sciences Institute of Dermatology and the National Center for STD Control on 9 October 2021 (approval number 2021-KY-037). The study is based on voluntary participation and a written informed consent process. The study results will be submitted for publication in peer-reviewed journals and reported in conferences. The relevant data will be made available to development of control programmes and used as health education materials to disseminate to the community. The dataset will be deposited in a public repository.
ChiCTR2100052869.
（CT）是世界上最常见的细菌性性传播感染，男男性行为者（MSM）被认为是这种感染的高危人群。中国关于 CT 感染流行率的数据有限且零散。在这项研究中，我们旨在确定全国范围内 MSM 中 CT 感染的解剖特异性流行率以及 CT 株的基因型分布，通过在 MSM 通常寻求性伴侣的场所招募参与者。
这项研究将是一项全国性的横断面调查，以在 6 个月（2022 年 5 月至 10 月）的时间内估计符合纳入标准的 MSM 中衣原体感染的流行率。将从中国 7 个地理区域的 14 个城市中 MSM 最常寻求性伴侣的场所招募 2429 名参与者。将使用基于移动电话应用程序的匿名自我管理问卷收集社会人口统计学和行为数据，并采集尿液、肛门直肠和咽拭子标本，以确定 CT 和 感染以及 CT 的基因型。将使用 IBM SPSS 程序 V.20 分析数据。
该研究方案已于 2021 年 10 月 9 日获得中国医学科学院皮肤病研究所和国家性病控制中心的医学伦理委员会批准（批准号 2021-KY-037）。该研究基于自愿参与和书面知情同意过程。研究结果将提交给同行评议期刊发表，并在会议上报告。相关数据将用于制定控制方案，并用作向社区传播的健康教育材料。数据集将存储在公共存储库中。
ChiCTR2100052869。
