Chu Yi-Ching, Huang Tzu-Lun, Chang Pei-Yao, Ho Wei-Ting, Hsu Yung-Ray, Chang Shu-Wen, Wang Jia-Kang
Department of Ophthalmology, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Department of Electrical Engineering, Yuan Ze University, Taoyuan, Taiwan.
Front Med (Lausanne). 2022 Apr 8;9:762761. doi: 10.3389/fmed.2022.762761. eCollection 2022.
To investigate the accuracy of 6 intraocular lens (IOL) power calculation formulas in predicting refractive outcomes in extremely long eyes.
Department of Ophthalmology, Far Eastern Memorial Hospital, Taiwan.
Retrospective comparative study.
In this retrospective single-center study, we reviewed 70 eyes of 70 patients with axial length (AL) ≥ 28 mm who had received an uneventful 2.2 mm corneal wound phacoemulsification and in-the-bag IOL placement. The actual postoperative refractive results were compared to the predicted refraction calculated with 6 formulas (Haigis, Hoffer Q, Holladay 1, SRK/T, T2, Barrett Universal II formulas) using IOLMaster 500 as optical biometry in the User Group for Laser Interference Biometry (ULIB) constants.
Overall, the Haigis and Barrett formulas achieved the lowest level of mean prediction error (PE) and median absolute error (MedAE). Hoffer Q, Holladay 1, SRK/T, and T2 had hyperopic prediction errors ( < 0.05). The Hoffer Q and Holladay 1 had significantly more MedAE between the 6 formulas. After the mean PE was zeroed out, the MedAE had no significant difference between each group. The absolute error tends to be larger in patients with longer AL. The absolute errors were 30.0-37.1% and 60.0-64.3% within 1.0 D of all patients compared to predicted refraction calculated using various formulas.
The Haigis and Barrett Universal II formulas had a better success rate in predicting IOL power in high myopic eyes with AL longer than 28 mm using the ULIB constant in this study. The postoperative refractive results were inferior to the benchmark standards, which indicated that the precision of IOL power calculation in patients with high myopia still required improvement.
研究6种人工晶状体（IOL）屈光度计算公式在预测极长眼屈光结果方面的准确性。
台湾远东纪念医院眼科。
回顾性比较研究。
在这项回顾性单中心研究中，我们回顾了70例眼轴长度（AL）≥28 mm的患者的70只眼睛，这些患者接受了顺利的2.2 mm角膜切口白内障超声乳化吸除术及囊袋内人工晶状体植入术。使用IOLMaster 500作为光学生物测量仪，并采用激光干涉生物测量用户组（ULIB）常数，将实际术后屈光结果与用6种公式（Haigis、Hoffer Q、Holladay 1、SRK/T、T2、Barrett通用II公式）计算出的预测屈光度进行比较。
总体而言，Haigis公式和Barrett公式的平均预测误差（PE）和中位数绝对误差（MedAE）水平最低。Hoffer Q、Holladay 1、SRK/T和T2公式存在远视预测误差（P<0.05）。在这6种公式中，Hoffer Q和Holladay 1公式的MedAE显著更大。在将平均PE归零后，各组之间的MedAE无显著差异。眼轴较长的患者绝对误差往往更大。与使用各种公式计算的预测屈光度相比，所有患者在1.0 D范围内的绝对误差为30.0% - 37.1%和60.0% - 64.3%。
在本研究中，使用ULIB常数时，Haigis公式和Barrett通用II公式在预测眼轴长度超过28 mm的高度近视眼中人工晶状体屈光度方面成功率更高。术后屈光结果低于基准标准，这表明高度近视患者人工晶状体屈光度计算的精度仍需提高。
