Jahnke Constantin, Doeblin Patrick, Tanacli Radu, Witt Undine, Schneider Matthias, Stehning Christian, Pieske Burkert, Kelle Sebastian
Department of Cardiology, German Heart Centre Berlin, Berlin, Germany.
German Centre for Cardiovascular Research DZHK, Partner Site Berlin, Berlin, Germany.
Front Cardiovasc Med. 2022 Apr 8;9:829392. doi: 10.3389/fcvm.2022.829392. eCollection 2022.
Serious adverse events associated with new vaccines targeting SARS-CoV-2 are of high interest to the public and to public health as a worldwide mass immunization campaign has been initiated to contain the ongoing COVID-19 pandemic. We describe a series of 4 individuals with signs of a myocarditis/pericarditis according to cardiac MRI results in temporal association with currently in the European Union authorized SARS-CoV-2 vaccines. We found mild abnormal MRI results independent of the type of SARS-CoV-2 vaccine. There is a need of continuing monitoring outcomes of myocarditis cases after COVID-19 vaccination as recently published cases suggest an uncomplicated short-term course whereas the long-term implications are not yet known but taking the available evidence into account the benefits of using COVID-19 vaccines still clearly outweigh the risks.
随着全球范围内为控制新冠疫情而开展大规模免疫接种运动，针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的新型疫苗相关的严重不良事件受到公众和公共卫生领域的高度关注。根据心脏磁共振成像（MRI）结果，我们描述了4例与目前在欧盟获批的SARS-CoV-2疫苗存在时间关联的心肌炎/心包炎症状患者。我们发现MRI结果轻度异常，且与SARS-CoV-2疫苗类型无关。鉴于最近公布的病例表明新冠疫苗接种后心肌炎病例短期病程不复杂，而长期影响尚不清楚，但综合现有证据，使用新冠疫苗的益处仍明显大于风险，因此有必要持续监测新冠疫苗接种后心肌炎病例的转归情况。
