Ochs Marco M, Haass Markus, Hagstotz Saskia, Giusca Sorin, Korosoglou Grigorios
Theresienkrankenhaus, Department of Cardiology, Angiology, and Intensive Care, Mannheim, Germany.
Department of Cardiology, GRN Hospital Weinheim, Weinheim, Germany.
Front Cardiovasc Med. 2022 Aug 17;9:990108. doi: 10.3389/fcvm.2022.990108. eCollection 2022.
During the worldwide ongoing immunization campaign against SARS-CoV-2, growing data on very rare but potentially harmful side effects of such vaccines arise since approval trials have not been adequately powered to detect those events. Besides the already reported vaccine-related myocarditis, which primarily occurs in young male individuals, our attention was recently drawn to a series of older male and female patients, who were referred to our institutions with isolated acute pericarditis without myocardial damage, shortly after SARS-CoV-2 vaccination. We describe a series of five adult patients presenting with chest pain, shortness of breath and isolated pericarditis with and without pericardial effusion after SARS-CoV-2 vaccination. All patients underwent echocardiography and cardiac magnetic resonance, and the corresponding findings, including late gadolinium enhancement (LGE) and T1 and T2 mapping are reported herein. To our knowledge, such cases have not been systematically reported in the current literature so far.
在全球正在进行的针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的免疫接种运动中，自疫苗获批以来，关于此类疫苗非常罕见但可能有害的副作用的数据不断增加，因为批准试验没有足够的能力检测到这些事件。除了已经报道的主要发生在年轻男性个体中的疫苗相关心肌炎外，最近我们的注意力被吸引到一系列老年男性和女性患者身上，他们在接种SARS-CoV-2疫苗后不久，因孤立性急性心包炎且无心肌损伤而被转诊至我们的机构。我们描述了5例成年患者，他们在接种SARS-CoV-2疫苗后出现胸痛、呼吸急促以及伴有或不伴有心包积液的孤立性心包炎。所有患者均接受了超声心动图和心脏磁共振检查，本文报告了相应的检查结果，包括钆延迟强化（LGE）以及T1和T2映射。据我们所知，目前文献中尚未对此类病例进行系统报道。
