Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Neonatal Unit, Karolinska University Hospital, Stockholm, Sweden.
Acta Paediatr. 2022 Aug;111(8):1507-1514. doi: 10.1111/apa.16371. Epub 2022 Apr 28.
Our aim was to investigate what effect immediate skin-to-skin contact with a parent had on the cardiorespiratory stabilisation of very preterm infants.
This randomised clinical trial was conducted during 2018-2021 at two university hospitals with three neonatal intensive care units in Norway and Sweden. Infants born from 28+0 to 32+6 weeks of gestation were randomised to immediate skin-to-skin contact with a parent for the first six postnatal hours or standard incubator care. The outcome was a composite cardiorespiratory stability score, based on serial measures of heart and respiratory rate, respiratory support, fraction of inspired oxygen and oxygen saturation.
We recruited 91 newborn infants with a mean gestational age of 31+1 (range 28+4-32+6) weeks and mean birth weight of 1534 (range 555-2440) g: 46 received immediate skin-to-skin contact and 45 received incubator care. The group who received skin-to-skin contact had an adjusted mean score of 0.52 higher (95% confidence interval 0.38-0.67, p < 0.001) on a scale from zero to six when compared to the control group.
Immediate skin-to-skin contact for the first six postnatal hours had beneficial effects on the cardiorespiratory stabilisation of very preterm infants.
本研究旨在探讨与父母进行即刻皮肤接触对极早产儿心肺复苏稳定的影响。
本随机临床试验于 2018 年至 2021 年在挪威和瑞典的两所大学医院的 3 个新生儿重症监护病房进行。将 28+0 至 32+6 周妊娠出生的婴儿随机分为在出生后 6 小时内与父母进行即刻皮肤接触或接受标准孵化器护理。主要结局为基于心率和呼吸频率、呼吸支持、吸入氧分数和氧饱和度的连续测量的复合心肺稳定评分。
共纳入 91 名新生儿,平均胎龄为 31+1 周(范围为 28+4-32+6 周),平均出生体重为 1534 克(范围为 555-2440 克):46 名接受即刻皮肤接触,45 名接受孵化器护理。与对照组相比,接受皮肤接触组的调整平均评分高 0.52 分(95%置信区间为 0.38-0.67,p<0.001),评分范围为 0 至 6。
出生后 6 小时内即刻皮肤接触对极早产儿的心肺复苏稳定有有益影响。