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骨髓纤维化中的免疫复合物:一种可能的治疗指导

Immune complexes in myelofibrosis: a possible guide to management.

作者信息

Lewis C M, Pegrum G D

出版信息

Br J Haematol. 1978 Jun;39(2):233-9. doi: 10.1111/j.1365-2141.1978.tb01093.x.

DOI:10.1111/j.1365-2141.1978.tb01093.x
PMID:354685
Abstract

Using a fluorescent technique intracellular immune complexes were found in the peripheral leucocytes in all of 12 patients with myelofibrosis studied. Fluorescent cells varied from 12% to 81%; with no relation to the total white count or any obvious clinical finding. Three of the patients with severe refractory anaemia benefited from immunosuppressive therapy.

摘要

采用荧光技术,在所研究的12例骨髓纤维化患者的外周血白细胞中均发现了细胞内免疫复合物。荧光细胞占比从12%到81%不等;与白细胞总数或任何明显的临床发现均无关联。3例重度难治性贫血患者从免疫抑制治疗中获益。

相似文献

1
Immune complexes in myelofibrosis: a possible guide to management.骨髓纤维化中的免疫复合物:一种可能的治疗指导
Br J Haematol. 1978 Jun;39(2):233-9. doi: 10.1111/j.1365-2141.1978.tb01093.x.
2
Immune complexes in myeloproliferative disorders.骨髓增殖性疾病中的免疫复合物。
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Subclinical immune complexes in the glomeruli of kidneys postmortem.死后肾脏肾小球中的亚临床免疫复合物。
Am J Med. 1974 Oct;57(4):536-41. doi: 10.1016/0002-9343(74)90003-5.
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Idiopathic myelofibrosis: a possible role for immune-complexes in the pathogenesis of bone marrow fibrosis.
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[Phagocytosis of immune complexes. Its diagnostic and pathological role in idiopathic myelofibrosis (author's transl)].[免疫复合物的吞噬作用。其在特发性骨髓纤维化中的诊断和病理作用(作者译)]
Sangre (Barc). 1981;26(5-A):567-74.
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[An autopsy case of primary myelofibrosis with high value of circulating immune complexes, IgG(kappa) monoclonal gammopathy and extramedullary hematopoietic subcutaneous tumors].[一例原发性骨髓纤维化尸检病例,伴有高循环免疫复合物水平、IgG(κ)单克隆丙种球蛋白病及髓外造血性皮下肿瘤]
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Idiopathic myelofibrosis: a possible role of immunological phenomena.
Br J Haematol. 1982 Feb;50(2):375-6. doi: 10.1111/j.1365-2141.1982.tb01929.x.
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A study of the cellular and humoral immune response in patients with myelofibrosis.骨髓纤维化患者细胞免疫和体液免疫反应的研究
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Immunological abnormalities in myelofibrosis.骨髓纤维化中的免疫异常。
Prog Clin Biol Res. 1984;154:455-63.
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[Detection of immune complex in the cytoplasma of peripheral blood leucocytes by the immunofluorescence technique (author's transl)].免疫荧光技术检测外周血白细胞胞浆中的免疫复合物(作者译)
Ryumachi. 1979 Oct;19(5):431-8.

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Immune derangements in patients with myelofibrosis: the role of Treg, Th17, and sIL2Rα.骨髓纤维化患者的免疫紊乱:调节性T细胞、辅助性T细胞17和可溶性白细胞介素2受体α的作用
PLoS One. 2015 Mar 20;10(3):e0116723. doi: 10.1371/journal.pone.0116723. eCollection 2015.
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An immune dysregulation in MPN.骨髓增殖性肿瘤中的免疫失调。
Curr Hematol Malig Rep. 2014 Dec;9(4):331-9. doi: 10.1007/s11899-014-0227-0.
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How should we manage myelofibrosis?我们应该如何治疗骨髓纤维化?
J R Coll Physicians Lond. 1981 Jan;15(1):17-8.
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Immune abnormalities in myelodysplastic syndromes.骨髓增生异常综合征中的免疫异常。
J Clin Pathol. 1985 Aug;38(8):908-11. doi: 10.1136/jcp.38.8.908.
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Composition of immune complexes and their relation to plasma fibronectin in chronic myeloproliferative disorders.慢性骨髓增殖性疾病中免疫复合物的组成及其与血浆纤连蛋白的关系。
J Clin Pathol. 1987 Dec;40(12):1468-71. doi: 10.1136/jcp.40.12.1468.
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Monoclonal gammopathy in chronic myeloproliferative disorders.
Blut. 1989 Jan;58(1):7-9. doi: 10.1007/BF00320228.
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Histomorphometry of bone marrow biopsies in primary osteomyelofibrosis/-sclerosis (agnogenic myeloid metaplasia)--correlations between clinical and morphological features.原发性骨髓纤维化/硬化症(特发性髓样化生)骨髓活检的组织形态计量学——临床与形态学特征之间的相关性
Virchows Arch A Pathol Anat Histopathol. 1989;415(3):191-202. doi: 10.1007/BF00724905.