Int J Periodontics Restorative Dent. 2022 May-Jun;42(3):419-427. doi: 10.11607/prd.5590.
Since the introduction of guided bone regeneration (GBR) using nonresorbable membranes, membrane exposure has been categorized as one of the major complications associated with the procedure. Expanded polytetrafluoroethylene (e-PTFE) has a long history of use in GBR, and now the use of high-density PTFE (d-PTFE) is commonly reported in the literature. The major structural difference between these two materials is their permeability to bacteria: e-PTFE has an open-pore microstructure and is permeable to bacteria, while d-PTFE is not. Thus, there are fundamental differences in the two materials if premature exposure occurs. Protocols for classification and management of exposure specific to e-PTFE have been published and were well-received by clinicians, but these protocols do not necessarily apply to d-PTFE exposures. Because of the fundamental structural differences between these two PTFE materials, a protocol specific to the classification and management of d-PTFE membrane healing complications is required and is thus presented in this paper.
自从使用不可吸收膜引入引导骨再生（GBR）以来，膜暴露已被归类为与该手术相关的主要并发症之一。膨体聚四氟乙烯（e-PTFE）在 GBR 中的使用历史悠久，现在文献中常报道使用高密度聚四氟乙烯（d-PTFE）。这两种材料的主要结构差异在于其对细菌的通透性：e-PTFE 具有开放的微孔结构，可允许细菌通过，而 d-PTFE 则不行。因此，如果发生过早暴露，两种材料在性质上存在根本差异。已经发表了针对 e-PTFE 特定的分类和管理的暴露方案，并且受到临床医生的欢迎，但这些方案不一定适用于 d-PTFE 暴露。由于这两种 PTFE 材料在结构上存在根本差异，因此需要针对 d-PTFE 膜愈合并发症的分类和管理制定专门的方案，本文对此进行了介绍。
