Department of Paediatrics, Sahlgrenska University Hospital, Gothenburg, Sweden.
Acta Paediatr. 2022 Aug;111(8):1596-1602. doi: 10.1111/apa.16372. Epub 2022 May 2.
(1) To explore the adherence of recommendations of vitamin D supplementation to children aged 0-4 years. (2) To compare serum levels of vitamin D in children and adolescents aged 0-17 years originating from different parts of the world. (3) To compare levels between boys and girls and (4) To determine seasonal variation.
A review of vitamin D levels in children with parents from different parts of the world was conducted. 2502 children aged 0-17 years were included between 22 January 2004 and 17 May 2021.
Fifty-nine of 363 children aged 0-4 years received the recommended vitamin D supplementation. Children from all parts of the world had lower levels of serum 25(OH)D than Swedish children. Girls from the Indian subcontinent, Middle East and Africa had the lowest levels of s-25(OH)D. Seasonal variation with higher levels during the summer was seen in children from Sweden, the rest of Europe, Russia and Latin America. Overall prevalence of vitamin D deficiency (≤25 nmol/L) was 928/2198 (42%) in children not receiving supplementation. Seven children had clinical rickets.
Adherence of giving children aged 0-4 years the recommended vitamin D supplementation was very low. Vitamin D deficiency is common in immigrant children of all ages in Sweden.
（1）探索 0-4 岁儿童维生素 D 补充建议的依从性。（2）比较来自世界不同地区的 0-17 岁儿童和青少年的血清维生素 D 水平。（3）比较男孩和女孩之间的水平，（4）确定季节性变化。
对来自世界不同地区的父母的儿童维生素 D 水平进行了综述。纳入了 2004 年 1 月 22 日至 2021 年 5 月 17 日期间 0-17 岁的 2502 名儿童。
363 名 0-4 岁儿童中有 59 名接受了推荐的维生素 D 补充。来自世界各个地区的儿童血清 25(OH)D 水平均低于瑞典儿童。来自印度次大陆、中东和非洲的女孩血清 25(OH)D 水平最低。来自瑞典、欧洲其他地区、俄罗斯和拉丁美洲的儿童在夏季血清 25(OH)D 水平较高，呈现季节性变化。未接受补充的儿童维生素 D 缺乏（≤25nmol/L）总体患病率为 928/2198（42%）。7 名儿童出现临床佝偻病。
0-4 岁儿童推荐补充维生素 D 的依从性非常低。维生素 D 缺乏在瑞典所有年龄段的移民儿童中都很常见。
