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[Methods of enhancing the radioprotective efficacy of serum immunoglobulin].

作者信息

Shal'nova G A, Klemparskaia N N, Kuz'mina T D, Ulanova A M, Ivanov A A

出版信息

Radiobiologiia. 1987 Jan-Feb;27(1):118-21.

PMID:3547459
Abstract

In this work the authors propose three ways of increasing the radioprotective efficiency of immunoglobulin: in vitro irradiation with gamma-quanta (60Co, 20,000 Gy), increasing the time of storage of whole blood (raw material for immunoglobulin production) up to 5-7 days at +4 degrees C, and the application of immunoglobulin with antibiotics. In experiments in vitro it was first shown that a combination of immunoglobulin with gentamicin exerted a pronounced bactericidal effect on E. coli. The effect was absent with immunoglobulin and markedly less pronounced with gentamicin used separately.

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