Shal'nova G A, Klemparskaia N N, Kuz'mina T D, Ulanova A M, Ivanov A A
Radiobiologiia. 1987 Jan-Feb;27(1):118-21.
In this work the authors propose three ways of increasing the radioprotective efficiency of immunoglobulin: in vitro irradiation with gamma-quanta (60Co, 20,000 Gy), increasing the time of storage of whole blood (raw material for immunoglobulin production) up to 5-7 days at +4 degrees C, and the application of immunoglobulin with antibiotics. In experiments in vitro it was first shown that a combination of immunoglobulin with gentamicin exerted a pronounced bactericidal effect on E. coli. The effect was absent with immunoglobulin and markedly less pronounced with gentamicin used separately.
在这项研究中，作者提出了三种提高免疫球蛋白辐射防护效率的方法：用γ量子（60Co，20,000 Gy）进行体外照射，将全血（免疫球蛋白生产的原料）在+4℃下储存的时间延长至5 - 7天，以及将免疫球蛋白与抗生素联合使用。在体外实验中，首次表明免疫球蛋白与庆大霉素联合使用对大肠杆菌具有显著的杀菌作用。单独使用免疫球蛋白时无此效果，单独使用庆大霉素时效果明显较弱。
