Universidade Federal do Pará. Faculdade de Medicina. Belém, PA, Brasil.
Centro Universitário do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil.
Rev Saude Publica. 2022 Apr 22;56:25. doi: 10.11606/s1518-8787.2022056003789. eCollection 2022.
To characterize the profile of inpatients and trend of sepsis mortality in the Brazilian Unified Health System (SUS), throughout Brazil, and in its regions separately, from 2010 to 2019.
Observational, analytical and retrospective study of secondary data obtained through consultation to the Sistema de Informação Hospitalar (Hospital Information System). All incoming septicemia notifications from January 1, 2010 to December 31, 2019 were included. The following sociodemographic variables were used: sex, age, race, region and federative unit of residence. For data analysis, we used mortality and hospitalization coefficient, relative risk and Joinpoint regression.
There were a total of 1,044,227 cases of sepsis in Brazil, yielding a mean prevalence coefficient of 51.3/100 thousand inhabitants. There were 463,000 deaths from sepsis recorded, with a mean prevalence coefficient of 22.8 deaths/100,000 inhabitants. The highest rates occurred among the elderly, of brown race, and there was no significant difference between genders. The Southeast region accounted for the highest rates of hospitalization and deaths. A general trend toward increased mortality was observed in the period studied.
The heterogeneity of Brazil should be considered regarding socioeconomic and demographic characteristics, and differences in health investment and underreporting between regions, in order to understand the disease's epidemiological course. Finally, these findings should be correlated with other studies, in an effort to understand the behavior of the disease, and provide inputs for public and private policies in order to reduce the expressiveness of cases and deaths from sepsis in Brazil.
描述巴西统一卫生系统（SUS）住院患者特征和脓毒症死亡率趋势，分析 2010 年至 2019 年期间巴西全国及各地区的情况。
本研究为观察性、分析性和回顾性研究，使用二次数据分析，数据来源于医院信息系统（Sistema de Informação Hospitalar）。纳入 2010 年 1 月 1 日至 2019 年 12 月 31 日所有新诊断为败血症的病例。使用的社会人口学变量包括：性别、年龄、种族、地区和居住的联邦单位。数据分析采用死亡率和住院率系数、相对风险和 Joinpoint 回归。
巴西共有 1044227 例败血症患者，平均患病率系数为 51.3/10 万居民。记录到 463000 例败血症死亡，平均死亡率为 22.8/10 万居民。死亡率最高的是老年人，棕色人种，性别之间无显著差异。东南部地区的住院率和死亡率最高。研究期间，死亡率呈总体上升趋势。
应考虑巴西的社会经济和人口特征的异质性，以及各地区之间卫生投资和漏报的差异，以了解疾病的流行病学过程。最后，这些发现应与其他研究相关联，以了解疾病的行为，并为公共和私人政策提供投入，以减少巴西败血症病例和死亡的发生率。
