Digestive Surgery Unit, Department of Surgery, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy; Università Cattolica del Sacro Cuore di Roma, Largo Francesco Vito 1, 00168, Rome, Italy.
Digestive Surgery Unit, Department of Surgery, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy.
Am J Surg. 2022 Nov;224(5):1209-1214. doi: 10.1016/j.amjsurg.2022.04.019. Epub 2022 Apr 22.
Few evidences are available on adhesive bowel obstruction (ASBO)management and outcomes in geriatric patients.
One-hundred-twenty-eight patients aged 65-79 years were retrospectively compared to 77 patients aged ≥80 years. Aim of this study was to compare ASBO management and in-hospital course between patients aged 65-79 years and those over 80 years.
Upfront surgery in octogenarians related with a higher rate of major complications (23.7%vs4.9%; p = 0.009) and longer hospitalization (8.8vs7.3 days; p = 0.01). No difference according to age was noted in terms of clinical outcomes when the non-operative management (NOM) was employed. Patients aged ≥80 years managed conservatively presented shorter hospitalization (7.3vs8.8 days; p = 0.04), lower rate of intensive care unit (ICU)admission (0vs18.4%; p = 0.005) and cumulative major complications (2.6%vs23.7%; p = 0.007) as compared to ≥80 years old patients treated with upfront surgery. In this same group, NOM failure did not lead to worse outcomes in comparison to upfront surgery.
NOM in≥80 years patients is associated with better in-hospital course. The acceptable clinical outcomes in case of NOM failure further support NOM as first treatment strategy to employ in this same subset of patients.
老年人粘连性肠梗阻(ASBO)的治疗和结局的证据有限。
回顾性比较了 128 名 65-79 岁的患者和 77 名≥80 岁的患者。本研究的目的是比较 65-79 岁和≥80 岁患者的 ASBO 治疗和住院过程。
80 岁以上患者行手术治疗的主要并发症发生率(23.7%对 4.9%;p=0.009)和住院时间(8.8 对 7.3 天;p=0.01)均较高。采用非手术治疗(NOM)时,两组在临床结局方面无年龄差异。≥80 岁的保守治疗患者的住院时间(7.3 对 8.8 天;p=0.04)、入住重症监护病房(ICU)的比例(0 对 18.4%;p=0.005)和累积主要并发症发生率(2.6%对 23.7%;p=0.007)均低于行手术治疗的≥80 岁患者。在同一组中,NOM 失败与手术治疗相比并未导致更差的结局。
NOM 治疗≥80 岁患者可改善住院过程。NOM 失败的可接受临床结局进一步支持 NOM 作为同一患者亚组的首选治疗策略。